Role of iodine in antioxidant defence in thyroid and breast disease

PPA Smyth - Biofactors, 2003 - Wiley Online Library
The role played in thyroid hormonogenesis by iodide oxidation to iodine (organification) is
well established. Iodine deficiency may produce conditions of oxidative stress with high TSH …

The thyroid, iodine and breast cancer

PPA Smyth - Breast Cancer Research, 2003 - Springer
A renewal of the search for a link between breast cancer and thyroid disease has once
again demonstrated an increased prevalence of autoimmune thyroid disease in patients …

Breast cancer in association with thyroid disorders

O Turken, Y NarIn, S DemIrbas, ME Onde… - Breast Cancer …, 2003 - Springer
Background The relationship between breast cancer and thyroid diseases is controversial.
Discrepant results have been reported in the literature. The incidences of autoimmune and …

Hypothyroidism and hyperthyroidism and breast cancer risk: a nationwide cohort study

M Søgaard, DK Farkas, V Ehrenstein… - European journal of …, 2016 - academic.oup.com
Objective The association between thyroid disease and breast cancer risk remains unclear.
We, therefore examined the association between hypothyroidism, hyperthyroidism and …

Effects of thyroid hormones on human breast cancer cell proliferation

LC Hall, EP Salazar, SR Kane, N Liu - The Journal of steroid biochemistry …, 2008 - Elsevier
The involvement of estrogens in breast cancer development and growth has been well
established. However, the effects of thyroid hormones and their combined effects with …

Benign thyroid disease is associated with breast cancer: a meta-analysis

PJ Hardefeldt, GD Eslick, S Edirimanne - Breast cancer research and …, 2012 - Springer
The controversial relationship between benign thyroid diseases and breast cancer (BC) has
been investigated for over 50 years. Despite extensive population studies, the results as a …

Serum thyroid peroxidase autoantibodies, thyroid volume, and outcome in breast carcinoma

PPA Smyth, SG Shering, MT Kilbane… - The Journal of …, 1998 - academic.oup.com
abstract The prevalence of thyroid peroxidase autoantibodies (TPO. Ab) was assessed in
patients with either breast carcinoma or benign breast disease, and its association with …

Prospectively measured thyroid hormones and thyroid peroxidase antibodies in relation to breast cancer risk

A Tosovic, C Becker, AG Bondeson… - … journal of cancer, 2012 - Wiley Online Library
Thyroid hormones influence both normal breast cell differentiation and breast cancer cell
proliferation and stimulate the angiogenesis of certain cancer forms. Several cross‐sectional …

Expression of thyroid hormone receptor/erbA genes is altered in human breast cancer

JM Silva, G Domínguez, JM González-Sancho… - Oncogene, 2002 - nature.com
The relation between thyroid status and diseases and cancer is unclear. No detailed
analysis of thyroid hormone receptor (TR) expression in human breast cancer has been …

[HTML][HTML] Iodine alters gene expression in the MCF7 breast cancer cell line: evidence for an anti-estrogen effect of iodine

FR Stoddard II, AD Brooks, BA Eskin… - International journal of …, 2008 - ncbi.nlm.nih.gov
The protective effects of iodine on breast cancer have been postulated from epidemiologic
evidence and described in animal models. The molecular mechanisms responsible have not …