Decreased skeletal muscle contractile activity (disuse) or unloading leads to muscle mass
loss, also known as muscle atrophy. The balance between muscle protein synthesis (MPS) …

Sarcopenia is a progressive systemic skeletal muscle disorder characterized by a
pathological decline in muscle strength, quantity, and quality, which frequently affects the …

Background Osteosarcopenia is a syndrome coexisting sarcopenia and osteopenia/
osteoporosis, with a high fracture risk. Recently, skeletal muscle and bone have been …

To mitigate the age-related decline in skeletal muscle quantity and quality, and the
associated negative health outcomes, it has been proposed that dietary protein …

As a result of advances in medical treatments and associated policy over the last century, life
expectancy has risen substantially and continues to increase globally. However, the …

Impairments in myofibrillar protein synthesis (MyoPS) during bed rest accelerate skeletal
muscle loss in older adults, increasing the risk of adverse secondary health outcomes. We …

Prehabilitation is a comprehensive preparation of a patient for primarily surgical treatments.
Its aim is to improve the patient's general condition so as to reduce the risk of complications …

Long-term immobilization of joints can lead to disuse atrophy of the muscles in the joints.
Oral nutrients are used clinically for rehabilitation and therapeutic purposes, but …

Cocoa flavanols have been shown to improve muscle function and may offer a novel
approach to protect against muscle atrophy. Hippuric acid (HA) is a colonic metabolite of (-) …

Short-term disuse leads to muscle loss driven by lowered daily myofibrillar protein synthesis
(MyoPS). However, disuse commonly results from muscle damage, and its influence on …