All biomaterials, when implanted in vivo, elicit cellular and tissue responses. These
responses include the inflammatory and wound healing responses, foreign body reactions …

The intestine contains the largest pool of macrophages in the body which are essential for
maintaining mucosal homeostasis in the face of the microbiota and the constant need for …

Macrophages (Mφs) are characterized by remarkable plasticity, an essential component of
chronic inflammation. Thus, an appropriate and timely transition from proinflammatory (M1) …

Summary Glutamine-synthetase (GS), the glutamine-synthesizing enzyme from glutamate,
controls important events, including the release of inflammatory mediators, mammalian …

Adverse cardiac remodeling after myocardial infarction (MI) causes structural and functional
changes in the heart leading to heart failure. The initial post-MI pro-inflammatory response …

Microglia mediate multiple facets of neuroinflammation, including cytotoxicity, repair,
regeneration, and immunosuppression due to their ability to acquire diverse activation …

Macrophages display remarkable plasticity and can change their physiology in response to
environmental cues. These changes can give rise to different populations of cells with …

Helminth parasites infect almost one-third of the world's population, primarily in tropical
regions. However, regions where helminth parasites are endemic record much lower …

The vertebrate immune system has evolved in concert with a broad range of infectious
agents, including ubiquitous helminth (worm) parasites. The constant pressure of helminth …

Polarization of macrophages to M1 or M2 cells is important for mounting responses against
bacterial and helminth infections, respectively. Jumonji domain containing-3 (Jmjd3), a …