MenTORing immunity: mTOR signaling in the development and function of tissue-resident immune cells

RG Jones, EJ Pearce - Immunity, 2017 - cell.com
Tissue-resident immune cells must balance survival in peripheral tissues with the capacity to
respond rapidly upon infection or tissue damage, and in turn couple these responses with …

Amino acid metabolism and signalling pathways: potential targets in the control of infection and immunity

D Tomé - Nutrition & Diabetes, 2021 - nature.com
Defences to pathogens such as SarCoV2 in mammals involves interactions between
immune functions and metabolic pathways to eradicate infection while preventing …

L-arginine metabolism as pivotal interface of mutual host–microbe interactions in the gut

B Nüse, T Holland, M Rauh, RG Gerlach, J Mattner - Gut Microbes, 2023 - Taylor & Francis
ABSTRACT L-arginine (L-arg) is a versatile amino acid and a central intestinal metabolite in
mammalian and microbial organisms. Thus, L-arg participates as precursor of multiple …

Nutrient Sensing and Biofilm Modulation: The Example of L-arginine in Pseudomonas

C Scribani Rossi, L Barrientos-Moreno… - International Journal of …, 2022 - mdpi.com
Bacterial biofilm represents a multicellular community embedded within an extracellular
matrix attached to a surface. This lifestyle confers to bacterial cells protection against hostile …

Lactobacillus plantarum ameliorates NASH-related inflammation by upregulating l-arginine production

DY Kim, JY Park, HY Gee - Experimental & Molecular Medicine, 2023 - nature.com
Lactobacillus is a probiotic with therapeutic potential for several diseases, including liver
disease. However, the therapeutic effect of L. plantarum against nonalcoholic steatohepatitis …

Cancer pharmacoprevention: Targeting polyamine metabolism to manage risk factors for colon cancer

EW Gerner, E Bruckheimer, A Cohen - Journal of Biological Chemistry, 2018 - ASBMB
Cancer is a set of diseases characterized by uncontrolled cell growth. In certain cancers of
the gastrointestinal tract, the adenomatous polyposis coli (APC) tumor suppressor gene is …

Dietary l-arginine Supplementation Alleviates the Intestinal Injury and Modulates the Gut Microbiota in Broiler Chickens Challenged by Clostridium perfringens

B Zhang, Z Lv, Z Li, W Wang, G Li, Y Guo - Frontiers in microbiology, 2018 - frontiersin.org
Our previous reports suggested that Dietary l-arginine supplementation attenuated gut injury
of broiler chickens infected with Clostridium perfringens by enhancing intestinal immune …

Nutrient stress is a target for new antibiotics

LA Carfrae, ED Brown - Trends in microbiology, 2023 - cell.com
Novel approaches are required to address the looming threat of pan-resistant Gram-
negative pathogens and forestall the rise of untreatable infections. Unconventional targets …

Polyamines in gut epithelial renewal and barrier function

JN Rao, L Xiao, JY Wang - Physiology, 2020 - journals.physiology.org
Polyamines regulate a variety of physiological functions and are involved in pathogenesis of
diverse human diseases. The epithelium of the mammalian gut mucosa is a rapidly self …

[HTML][HTML] Dietary l-arginine supplementation ameliorates inflammatory response and alters gut microbiota composition in broiler chickens infected with Salmonella …

B Zhang, G Li, MS Shahid, L Gan, H Fan, Z Lv, S Yan… - Poultry science, 2020 - Elsevier
This study was conducted to investigate the effects of dietary arginine (Arg) supplementation
on the inflammatory response and gut microbiota of broiler chickens subjected to …