Autophagy in major human diseases

DJ Klionsky, G Petroni, RK Amaravadi… - The EMBO …, 2021 - embopress.org
Autophagy is a core molecular pathway for the preservation of cellular and organismal
homeostasis. Pharmacological and genetic interventions impairing autophagy responses …

Autophagy in healthy aging and disease

Y Aman, T Schmauck-Medina, M Hansen, RI Morimoto… - Nature aging, 2021 - nature.com
Autophagy is a fundamental cellular process that eliminates molecules and subcellular
elements, including nucleic acids, proteins, lipids and organelles, via lysosome-mediated …

Autophagy in liver diseases: a review

H Qian, X Chao, J Williams, S Fulte, T Li, L Yang… - Molecular aspects of …, 2021 - Elsevier
The liver is a highly dynamic metabolic organ that plays critical roles in plasma protein
synthesis, gluconeogenesis and glycogen storage, cholesterol metabolism and bile acid …

The intersection between alcohol-related liver disease and nonalcoholic fatty liver disease

LA Díaz, JP Arab, A Louvet, R Bataller… - Nature Reviews …, 2023 - nature.com
Nonalcoholic fatty liver disease (NAFLD) and alcohol-related liver disease (ALD) are the
leading causes of chronic liver disease worldwide. NAFLD and ALD share …

The AMPK pathway in fatty liver disease

C Fang, J Pan, N Qu, Y Lei, J Han, J Zhang… - Frontiers in …, 2022 - frontiersin.org
Lipid metabolism disorders are the primary causes for the occurrence and progression of
various liver diseases, including non-alcoholic fatty liver disease (NAFLD) and alcoholic fatty …

Maresin1 protect against ferroptosis-induced liver injury through ROS inhibition and Nrf2/HO-1/GPX4 activation

W Yang, Y Wang, C Zhang, Y Huang, J Yu… - Frontiers in …, 2022 - frontiersin.org
Drugs, viruses, and chemical poisons stimulating live in a short period of time can cause
acute liver injury (ALI). ALI can further develop into serious liver diseases such as cirrhosis …

Autophagy in liver diseases: time for translation?

M Allaire, PE Rautou, P Codogno, S Lotersztajn - Journal of Hepatology, 2019 - Elsevier
Autophagy is a self-eating catabolic pathway that contributes to liver homeostasis through its
role in energy balance and in the quality control of the cytoplasm, by removing misfolded …

Recent advances in alcohol-related liver disease (ALD): summary of a Gut round table meeting

MA Avila, JF Dufour, AL Gerbes, F Zoulim, R Bataller… - Gut, 2020 - gut.bmj.com
Alcohol-related liver disease (ALD), which includes a range of disorders of different severity
and is one of the most prevalent types of liver disease worldwide, has recently regained …

[HTML][HTML] Artesunate alleviates liver fibrosis by regulating ferroptosis signaling pathway

Z Kong, R Liu, Y Cheng - Biomedicine & Pharmacotherapy, 2019 - Elsevier
Liver fibrosis is a progression of chronic liver disease, which lacks effective therapies in the
world. Attractively, more and more evidences show that natural products are safe and …

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1

DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif… - autophagy, 2021 - Taylor & Francis
In 2008, we published the first set of guidelines for standardizing research in autophagy.
Since then, this topic has received increasing attention, and many scientists have entered …