Lysine-specific histone demethylase 3 (KDM3) subfamily proteins are H3K9me2/me1
histone demethylases that promote gene expression. The KDM3 subfamily primarily consists …

Breast cancer remains the most frequently diagnosed cancer in women worldwide. Delayed
presentation of the disease, late stage at diagnosis, limited therapeutic options, metastasis …

Left ventricular hypertrophy (LVH) is a major risk factor for cardiovascular morbidity and
mortality. Pathological LVH engages transcriptional programs including reactivation of …

Accumulating evidence has suggested that extracellular vesicles (EVs) play a crucial role in
lung cancer treatment. Thus, we aimed to investigate the modulatory role of bone marrow …

Histone modifications (HMs) contribute to maintaining genomic stability, transcription, DNA
repair, and modulating chromatin in cancer cells. Furthermore, HMs are dynamic and …

Epigenetic changes are one underlying cause for cancer development and often due to
dysregulation of enzymes modifying DNA or histones. Most Jumonji C domain-containing …

Simple Summary Hypoxia—reduction in oxygen availability—plays key roles in both
physiological and pathological processes. Given the importance of oxygen for cell and …

Breast cancer (BC) is the most common malignant disease affecting women's health
worldwide. The benefits from conventional therapeutic modalities are severely limited. An …

MyoD family inhibitor (MDFI) and MDFI domain-containing (MDFIC) are homologous
proteins known to regulate myogenic transcription factors. Hitherto, their role in cancer is …

Emerging evidences have shown that Dihydroartemisinin (DHA), used in malaria treatment,
possess anti-cancer activity. However, the study of its potential functional roles and the anti …