SEDPHAT–a platform for global ITC analysis and global multi-method analysis of molecular interactions
Isothermal titration calorimetry experiments can provide significantly more detailed
information about molecular interactions when combined in global analysis. For example …
information about molecular interactions when combined in global analysis. For example …
[HTML][HTML] Use of isothermal titration calorimetry to study surfactant aggregation in colloidal systems
Background Isothermal titration calorimetry (ITC) is a general technique that allows for
precise and highly sensitive measurements. These measurements may provide a complete …
precise and highly sensitive measurements. These measurements may provide a complete …
Nuclear import receptor inhibits phase separation of FUS through binding to multiple sites
Liquid-liquid phase separation (LLPS) is believed to underlie formation of biomolecular
condensates, cellular compartments that concentrate macromolecules without surrounding …
condensates, cellular compartments that concentrate macromolecules without surrounding …
Calculations and publication-quality illustrations for analytical ultracentrifugation data
CA Brautigam - Methods in enzymology, 2015 - Elsevier
The analysis of analytical ultracentrifugation (AUC) data has been greatly facilitated by the
advances accumulated in recent years. These improvements include refinements in AUC …
advances accumulated in recent years. These improvements include refinements in AUC …
Integration and global analysis of isothermal titration calorimetry data for studying macromolecular interactions
Isothermal titration calorimetry (ITC) is a powerful and widely used method to measure the
energetics of macromolecular interactions by recording a thermogram of differential heating …
energetics of macromolecular interactions by recording a thermogram of differential heating …
Fuzzy recognition by the prokaryotic transcription factor HigA2 from Vibrio cholerae
Disordered protein sequences can exhibit different binding modes, ranging from well-
ordered folding-upon-binding to highly dynamic fuzzy binding. The primary function of the …
ordered folding-upon-binding to highly dynamic fuzzy binding. The primary function of the …
Molecular binding between anthocyanins and pectic polysaccharides–Unveiling the role of pectic polysaccharides structure
A Fernandes, J Oliveira, F Fonseca… - Food …, 2020 - Elsevier
The interaction between cyanidin-3-O-glucoside and four citrus pectic fractions was
investigated using a combined molecular approach, including isothermal titration calorimetry …
investigated using a combined molecular approach, including isothermal titration calorimetry …
Structural basis of p62/SQSTM1 helical filaments and their role in cellular cargo uptake
Abstract p62/SQSTM1 is an autophagy receptor and signaling adaptor with an N-terminal
PB1 domain that forms the scaffold of phase-separated p62 bodies in the cell. The molecular …
PB1 domain that forms the scaffold of phase-separated p62 bodies in the cell. The molecular …
Distinct homotypic B-cell receptor interactions shape the outcome of chronic lymphocytic leukaemia
C Minici, M Gounari, R Übelhart, L Scarfo… - Nature …, 2017 - nature.com
Cell-autonomous B-cell receptor (BcR)-mediated signalling is a hallmark feature of the
neoplastic B lymphocytes in chronic lymphocytic leukaemia (CLL). Here we elucidate the …
neoplastic B lymphocytes in chronic lymphocytic leukaemia (CLL). Here we elucidate the …
The Fab region of IgG impairs the internalization pathway of FcRn upon Fc engagement
M Brinkhaus, E Pannecoucke, EJ van der Kooi… - Nature …, 2022 - nature.com
Binding to the neonatal Fc receptor (FcRn) extends serum half-life of IgG, and antagonizing
this interaction is a promising therapeutic approach in IgG-mediated autoimmune diseases …
this interaction is a promising therapeutic approach in IgG-mediated autoimmune diseases …