Ethical issues when using digital biomarkers and artificial intelligence for the early detection of dementia

E Ford, R Milne, K Curlewis - Wiley Interdisciplinary Reviews …, 2023 - Wiley Online Library
Dementia poses a growing challenge for health services but remains stigmatized and under‐
recognized. Digital technologies to aid the earlier detection of dementia are approaching …

[HTML][HTML] The use of deep learning and machine learning on longitudinal electronic health records for the early detection and prevention of diseases: scoping review

L Swinckels, FC Bennis, KA Ziesemer… - Journal of Medical …, 2024 - jmir.org
Background Electronic health records (EHRs) contain patients' health information over time,
including possible early indicators of disease. However, the increasing amount of data …

Causal inference in medical records and complementary systems pharmacology for metformin drug repurposing towards dementia

ML Charpignon, B Vakulenko-Lagun, B Zheng… - Nature …, 2022 - nature.com
Metformin, a diabetes drug with anti-aging cellular responses, has complex actions that may
alter dementia onset. Mixed results are emerging from prior observational studies. To …

[HTML][HTML] A risk prediction model based on machine learning for cognitive impairment among Chinese community-dwelling elderly people with normal cognition …

M Hu, X Shu, G Yu, X Wu, M Välimäki… - Journal of medical Internet …, 2021 - jmir.org
Background Identifying cognitive impairment early enough could support timely intervention
that may hinder or delay the trajectory of cognitive impairment, thus increasing the chances …

Critical bias in critical care devices

ML Charpignon, J Byers, S Cabral… - Critical Care …, 2023 - criticalcare.theclinics.com
Critical care data reflect the most physiologically unstable patients in a hospital. These
patients are heavily monitored and may undergo complex treatment regimens to manage …

Influence of medical domain knowledge on deep learning for Alzheimer's disease prediction

B Ljubic, S Roychoudhury, XH Cao, M Pavlovski… - Computer methods and …, 2020 - Elsevier
Background and objective Alzheimer's disease (AD) is the most common type of dementia
that can seriously affect a person's ability to perform daily activities. Estimates indicate that …

Barriers and facilitators to the adoption of electronic clinical decision support systems: a qualitative interview study with UK general practitioners

E Ford, N Edelman, L Somers, D Shrewsbury… - BMC medical informatics …, 2021 - Springer
Background Well-established electronic data capture in UK general practice means that
algorithms, developed on patient data, can be used for automated clinical decision support …

Temporal trends in population attributable fractions of modifiable risk factors for dementia: a time-series study of the English Longitudinal Study of Ageing (2004–2019)

S Chen, BR Underwood, RN Cardinal, X Chen, S Chen… - BMC medicine, 2024 - Springer
Background Interest in modifiable risk factors (MRFs) for dementia is high, given the
personal, social, and economic impact of the disorder, especially in ageing societies such as …

Automated detection of patients with dementia whose symptoms have been identified in primary care but have no formal diagnosis: a retrospective case–control study …

E Ford, J Sheppard, S Oliver, P Rooney, S Banerjee… - BMJ open, 2021 - bmjopen.bmj.com
Objectives UK statistics suggest only two-thirds of patients with dementia get a diagnosis
recorded in primary care. General practitioners (GPs) report barriers to formally diagnosing …

[HTML][HTML] Electronic medical record–based case phenotyping for the charlson conditions: scoping review

S Lee, C Doktorchik, EA Martin… - JMIR medical …, 2021 - medinform.jmir.org
Background Electronic medical records (EMRs) contain large amounts of rich clinical
information. Developing EMR-based case definitions, also known as EMR phenotyping, is …