Hyperketonemia: A Marker of Disease, a Sign of a High-Producing Dairy Cow, or Both?
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[HTML][HTML] Pre-and postpartum metabolizable protein supply: I. Effects on feed intake, lactation performance, and metabolic markers in transition dairy cows
TA Westhoff, TR Overton, JN Tikofsky… - Journal of Dairy …, 2024 - Elsevier
The objective of this study was to investigate the effect of increasing MP supply in the
prepartum, postpartum, or both diets on intake, performance, and metabolic indicators …
prepartum, postpartum, or both diets on intake, performance, and metabolic indicators …
[HTML][HTML] Effects of dietary branched-chain amino acid supplementation on serum and milk metabolome profiles in dairy cows during early lactation
The 3 branched-chain AA (BCAA), Val, Leu, and Ile, are essential AA used by tissues as
substrates for protein synthesis and energy generation. In addition, BCAA are also involved …
substrates for protein synthesis and energy generation. In addition, BCAA are also involved …
[HTML][HTML] Lipopolysaccharide challenge following intravenous amino acid infusion in postpartum dairy cows: I. Production, metabolic, and hormonal responses
TL Chandler, TA Westhoff, TR Overton, AL Lock… - Journal of Dairy …, 2022 - Elsevier
Postpartum cows experience a nadir in energy and AA deficit early postpartum. At the same
time, cows are challenged with inflammatory stimuli and often show heightened immune …
time, cows are challenged with inflammatory stimuli and often show heightened immune …
The effect of the transition period and postpartum body weight loss on macrophage infiltrates in bovine subcutaneous adipose tissue
The transition period in dairy cattle is characterized by a rapid increase in metabolic
demands due to the onset of lactation in parallel with a voluntary drop in dry matter intake …
demands due to the onset of lactation in parallel with a voluntary drop in dry matter intake …
[HTML][HTML] Effect of rumen-protected branched-chain amino acid supplementation on production-and energy-related metabolites during the first 35 days in milk in …
Essential AA are critical for multiple physiological processes. Branched-chain AA (BCAA)
supplementation has beneficial effects on body weight, lipogenesis, and insulin resistance …
supplementation has beneficial effects on body weight, lipogenesis, and insulin resistance …
[HTML][HTML] Effect of close-up metabolizable protein supply on colostrum yield, composition, and immunoglobulin G concentration and associations with prepartum …
TA Westhoff, A Abuelo, TR Overton… - Journal of Dairy …, 2024 - Elsevier
The prepartum diet as well as individual metabolic status of the cow influences colostrum
parameters. The objectives of this study were to (1) investigate the effect of increasing …
parameters. The objectives of this study were to (1) investigate the effect of increasing …
[HTML][HTML] The effect of ex vivo lipopolysaccharide stimulation and nutrient availability on transition cow innate immune cell AKT/mTOR pathway responsiveness
AS Sipka, TL Chandler, EL Behling-Kelly… - Journal of dairy …, 2020 - Elsevier
Postpartum dairy cows experience a heightened inflammatory state coinciding with the time
of greatest nutrient deficit. Nutrient availability is sensed on the cellular level by nutrient …
of greatest nutrient deficit. Nutrient availability is sensed on the cellular level by nutrient …
[HTML][HTML] Comparative evaluation of 3 methods for the quantification of nonesterified fatty acids in bovine plasma sampled prepartum
A Abuelo, JL Brester, K Starken, LM Neuder - Journal of dairy science, 2020 - Elsevier
Serum or plasma concentrations of nonesterified fatty acids (NEFA) are commonly used as
biomarkers of lipolysis during the periparturient period in dairy cows. However, NEFA …
biomarkers of lipolysis during the periparturient period in dairy cows. However, NEFA …
[HTML][HTML] The use of ultrasonography in the transition period to estimate adipose tissue depots and their association with risk of early postpartum hyperketonemia in …
TA Westhoff, M Rodger, M Wieland, LA Harper… - JDS communications, 2025 - Elsevier
An elevated prepartum BCS is a risk factor for postpartum hyperketonemia (HYK) and
elevated nonesterified fatty acid (NEFA) concentrations in dairy cattle. The association …
elevated nonesterified fatty acid (NEFA) concentrations in dairy cattle. The association …