The multifaceted roles of proline in cell behavior

EJ Patriarca, F Cermola, C D'Aniello, A Fico… - Frontiers in cell and …, 2021 - frontiersin.org
Herein, we review the multifaceted roles of proline in cell biology. This peculiar cyclic imino
acid is:(i) A main precursor of extracellular collagens (the most abundant human proteins) …

Animal by-products collagen and derived peptide, as important components of innovative sustainable food systems—A comprehensive review

C Cao, Z Xiao, C Ge, Y Wu - Critical Reviews in Food Science and …, 2022 - Taylor & Francis
In 2020, the world's food crisis and health industry ushered into a real outbreak. On one
side, there were natural disasters such as the novel coronavirus (2019-nCoV), desert …

Collagen peptides supplementation improves function, pain, and physical and mental outcomes in active adults

SA Kviatkovsky, RC Hickner, HE Cabre… - Journal of the …, 2023 - Taylor & Francis
Introduction Chronic pain affects 19% of adults in the United States, with increasing
prevalence in active and aging populations. Pain can limit physical activity and activities of …

Modulating effects of zingiberaceae phenolic compounds on neurotrophic factors and their potential as neuroprotectants in brain disorders and age-associated …

AM Razak, JK Tan, M Mohd Said, S Makpol - Nutrients, 2023 - mdpi.com
The Zingiberaceae family possess various phenolic compounds that have significant
systemic bioactivities in the brain, including in age-related neurodegenerative diseases …

Collagen peptide supplementation before bedtime reduces sleep fragmentation and improves cognitive function in physically active males with sleep complaints

C Thomas, RN Kingshott, KM Allott, JCY Tang… - European Journal of …, 2024 - Springer
Purpose The primary aim of this study was to examine whether a glycine-rich collagen
peptides (CP) supplement could enhance sleep quality in physically active men with self …

Neuromodulatory peptides: Orally active anxiolytic-like and antidepressant-like peptides derived from dietary plant proteins

T Mizushige - Peptides, 2021 - Elsevier
Mental disorders are a severe health problem, and the number of patients is growing
worldwide. Increased anxiety and decreased motivation due to excessive mental stress …

Identification of monoamine oxidases inhibitory peptides from soybean protein hydrolysate through ultrafiltration purification and in silico studies

F Ying, S Lin, J Li, X Zhang, G Chen - Food Bioscience, 2021 - Elsevier
Monoamine oxidases (MAOs, including MAO-A and MAO-B) are essential deamination
enzymes for neurotransmitters and other amines; thus, they are potential targets for …

Prolyl‐hydroxyproline, a collagen‐derived dipeptide, enhances hippocampal cell proliferation, which leads to antidepressant‐like effects in mice

D Nogimura, T Mizushige, Y Taga, A Nagai… - The FASEB …, 2020 - Wiley Online Library
Depression has been a mental health issue worldwide. We previously reported that ginger‐
degraded collagen hydrolysate (GDCH) suppressed depression‐like behavior in mice …

[HTML][HTML] Food-derived protein hydrolysates and peptides: anxiolytic and antidepressant activities, characteristics, and mechanisms

W Li, Y Xi, J Wang, Y Zhang, H Li, X Liu - Food Science and Human …, 2024 - Elsevier
Globally, the prevalence of anxiety and depression has reached epidemic proportions. Food-
derived protein hydrolysates and peptides delivered through dietary supplementation can …

Identification of a highly stable bioactive 3-hydroxyproline-containing tripeptide in human blood after collagen hydrolysate ingestion

Y Taga, Y Iwasaki, C Tometsuka, N Funato… - npj Science of …, 2022 - nature.com
There are increasing reports demonstrating high bioavailability of 4-hydroxyproline (4Hyp)-
containing oligopeptides after oral ingestion of collagen hydrolysate and their bioactivity. In …