Biomedical applications of quaternized chitosan

K Pathak, SK Misra, A Sehgal, S Singh, S Bungau… - Polymers, 2021 - mdpi.com
The natural polymer chitosan is the second most abundant biopolymer on earth after chitin
and has been extensively explored for preparation of versatile drug delivery systems. The …

Anti-inflammatory therapeutic mechanisms of natural products: insight from rosemary diterpenes, carnosic acid and carnosol

S Habtemariam - Biomedicines, 2023 - mdpi.com
Carnosic acid (CA) and carnosol (CAR) are two major diterpenes of the rosemary plant
(Rosmarinus officinalis). They possess a phenolic structural moiety and are endowed with …

The growing concern of chlorpyrifos exposures on human and environmental health

NK Nandi, A Vyas, MJ Akhtar, B Kumar - Pesticide biochemistry and …, 2022 - Elsevier
Chlorpyrifos (CP) and its highly electrophilic intermediates are principal toxic metabolites.
The active form of CP ie chlorpyrifos oxon (CP-oxon) is responsible for both the insecticidal …

Chlorpyrifos triggers epithelioma papulosum cyprini cell pyroptosis via miR-124-3p/CAPN1 axis

Z Miao, Z Miao, X Teng, S Xu - Journal of hazardous materials, 2022 - Elsevier
Chlorpyrifos (CPF), a widely used organophosphorus pesticide has caused water pollution,
threatening aquatic organisms. MicroRNAs (miRNAs) highly conserved noncoding RNAs …

Antioxidant and anti-inflammatory potential of thymoquinone and lycopene mitigate the chlorpyrifos-induced toxic neuropathy

M Aboubakr, SM Elshafae, EY Abdelhiee, SE Fadl… - Pharmaceuticals, 2021 - mdpi.com
CPF (chlorpyrifos) is an organophosphate pesticide used in agricultural and veterinary
applications. Our experiment aimed to explore the effects of thymoquinone (TQ) and/or …

Oxidative stress and mitochondrial dysfunction in organophosphate pesticide-induced neurotoxicity and its amelioration: a review

T Farkhondeh, O Mehrpour, F Forouzanfar… - … Science and Pollution …, 2020 - Springer
Organophosphorus pesticides (OPs) are widely used for controlling pests worldwide. The
inhibitory effects of these pesticides on acetylcholinesterase lead to neurotoxic damages …

Morin protects against acrylamide-induced neurotoxicity in rats: an investigation into different signal pathways

C Gur, FM Kandemir, E Darendelioglu… - … Science and Pollution …, 2021 - Springer
The presented study investigates the effects of morin against toxicity induced by acrylamide
(ACR) in the brains of Sprague Dawley rats. In this study, neurotoxicity was induced by orally …

Chronic chlorpyrifos exposure induces oxidative stress, apoptosis and immune dysfunction in largemouth bass (Micropterus salmoides)

L Zhao, G Tang, C Xiong, S Han, C Yang, K He… - Environmental …, 2021 - Elsevier
This study was undertaken to (a) evaluate the destructive effects of chronic exposure to low-
dose of chlorpyrifos (CPF) on antioxidant system and immune function in largemouth bass …

Neuroprotective effects of carnosic acid: Insight into its mechanisms of action

FJ Mirza, S Zahid, RMD Holsinger - Molecules, 2023 - mdpi.com
Carnosic acid is a diterpenoid abundantly present in plants belonging to the genus
Rosmarinus and Salvia of the family Lamiaceae, accounting for their application in …

Effects of rosmarinic acid, carnosic acid, rosmanol, carnosol, and ursolic acid on the pathogenesis of respiratory diseases

F Farhadi, V Baradaran Rahimi, N Mohamadi… - Biofactors, 2023 - Wiley Online Library
This review aimed to identify preclinical and clinical studies examining the effects of
rosmarinic acid (RA), carnosic acid (CaA), rosmanol (RO), carnosol (CA), and ursolic acid …