Scientific, sustainability and regulatory challenges of cultured meat
Cellular agriculture is an emerging branch of biotechnology that aims to address issues
associated with the environmental impact, animal welfare and sustainability challenges of …
associated with the environmental impact, animal welfare and sustainability challenges of …
[HTML][HTML] Vascular tissue engineering: progress, challenges, and clinical promise
Although the clinical demand for bioengineered blood vessels continues to rise, current
options for vascular conduits remain limited. The synergistic combination of emerging …
options for vascular conduits remain limited. The synergistic combination of emerging …
Textured soy protein scaffolds enable the generation of three-dimensional bovine skeletal muscle tissue for cell-based meat
T Ben-Arye, Y Shandalov, S Ben-Shaul, S Landau… - Nature Food, 2020 - nature.com
Cell-based meat (CBM) production is a promising technology that could generate meat
without the need of animal agriculture. The generation of tissue requires a three …
without the need of animal agriculture. The generation of tissue requires a three …
Neural cell integration into 3D bioprinted skeletal muscle constructs accelerates restoration of muscle function
JH Kim, I Kim, YJ Seol, IK Ko, JJ Yoo, A Atala… - Nature …, 2020 - nature.com
A bioengineered skeletal muscle construct that mimics structural and functional
characteristics of native skeletal muscle is a promising therapeutic option to treat extensive …
characteristics of native skeletal muscle is a promising therapeutic option to treat extensive …
Biodegradable scaffold with built-in vasculature for organ-on-a-chip engineering and direct surgical anastomosis
We report the fabrication of a scaffold (hereafter referred to as AngioChip) that supports the
assembly of parenchymal cells on a mechanically tunable matrix surrounding a perfusable …
assembly of parenchymal cells on a mechanically tunable matrix surrounding a perfusable …
Tissue engineering for clean meat production
T Ben-Arye, S Levenberg - Frontiers in Sustainable Food Systems, 2019 - frontiersin.org
Increasing public awareness of foodborne illnesses, factory farming, and the ecological
footprint of the meat industry, has generated the need for animal-free meat alternatives. In …
footprint of the meat industry, has generated the need for animal-free meat alternatives. In …
Macrophages of diverse phenotypes drive vascularization of engineered tissues
Macrophages are key contributors to vascularization, but the mechanisms behind their
actions are not understood. Here, we show that diverse macrophage phenotypes have …
actions are not understood. Here, we show that diverse macrophage phenotypes have …
[HTML][HTML] Three-dimensional human iPSC-derived artificial skeletal muscles model muscular dystrophies and enable multilineage tissue engineering
SM Maffioletti, S Sarcar, ABH Henderson, I Mannhardt… - Cell Reports, 2018 - cell.com
Generating human skeletal muscle models is instrumental for investigating muscle
pathology and therapy. Here, we report the generation of three-dimensional (3D) artificial …
pathology and therapy. Here, we report the generation of three-dimensional (3D) artificial …
Materials roles for promoting angiogenesis in tissue regeneration
Enabling angiogenesis is critical for the success of tissue repair therapies and the fate of
tissue-engineered constructs. Although many biochemical signaling molecules have been …
tissue-engineered constructs. Although many biochemical signaling molecules have been …
Bioengineered constructs combined with exercise enhance stem cell-mediated treatment of volumetric muscle loss
M Quarta, M Cromie, R Chacon, J Blonigan… - Nature …, 2017 - nature.com
Volumetric muscle loss (VML) is associated with loss of skeletal muscle function, and current
treatments show limited efficacy. Here we show that bioconstructs suffused with genetically …
treatments show limited efficacy. Here we show that bioconstructs suffused with genetically …