Multiple pathways to functional impairment in obsessive–compulsive disorder

Y Markarian, MJ Larson, MA Aldea, SA Baldwin… - Clinical psychology …, 2010 - Elsevier
Obsessive–compulsive disorder (OCD) is a chronic and debilitating condition that is
relatively common in both children and adults, and it is associated with a wide range of …

Treatment of comorbid bipolar disorder and obsessive–compulsive disorder: a systematic review

A Amerio, A Odone, C Marchesi, SN Ghaemi - Journal of affective disorders, 2014 - Elsevier
Background More than 20% of patients with bipolar disorder (BD) show lifetime comorbidity
for obsessive–compulsive disorder (OCD), but treatment of BD–OCD is a clinical challenge …

Family burden, quality of life and disability in obsessive compulsive disorder: an Indian perspective

GP Gururaj, SB Math, JYC Reddy… - Journal of …, 2008 - journals.lww.com
Background: Obsessive compulsive disorder (OCD) is a psychiatric disorder that often tends
to run a chronic course. The lifetime prevalence of OCD is around 1-3%, which is twice as …

[HTML][HTML] Glutamatergic synaptic dysfunction and obsessive-compulsive disorder

JT Ting, G Feng - Current chemical genomics, 2008 - ncbi.nlm.nih.gov
Obsessive-compulsive disorder (OCD) is a debilitating neuropsychiatric condition estimated
to afflict 1-3% of the world population. The estimated financial impact in the treatment and …

Central 5-HT4 receptor binding as biomarker of serotonergic tonus in humans: a [11C] SB207145 PET study

ME Haahr, PM Fisher, CG Jensen, VG Frokjaer… - Molecular …, 2014 - nature.com
Identification of a biomarker that can inform on extracellular serotonin (5-HT) levels in the
brains of living humans would enable greater understanding of the way brain circuits are …

A preliminary examination of acceptance and commitment therapy versus exposure and response prevention for patients with obsessive-compulsive disorder on an …

M Zemestani, M Salavati… - Behavior …, 2022 - journals.sagepub.com
This study compared the effects of adding acceptance and commitment therapy (ACT) or
exposure and response prevention (ERP) to adults diagnosed with obsessive compulsive …

Quetiapine augments the effect of citalopram in non-refractory obsessive-compulsive disorder: a randomized, double-blind, placebo-controlled study of 76 patients.

NCC Vulink, D Denys, SB Fluitman… - Journal of clinical …, 2009 - psychiatrist.com
Objective: To assess the efficacy of quetiapine addition to citalopram in treatment-naive or
medication-free obsessive-compulsive disorder (OCD) patients. Method: Seventy-six …

Augmentation strategies in obsessive–compulsive disorder

SS Arumugham, JYC Reddy - Expert review of neurotherapeutics, 2013 - Taylor & Francis
Around 40–60% of patients with obsessive–compulsive disorder do not show adequate
response to selective serotonin reuptake inhibitors (SSRIs). Augmentation strategies are …

BDNF gene and obsessive compulsive disorder risk, symptom dimensions and treatment response

RJT MJ, S Ganesh, T Shukla, S Deolankar… - Asian journal of …, 2018 - Elsevier
Abstract Aim Genetic etiology of Obsessive Compulsive Disorder (OCD) has been
investigated extensively, with mixed results across candidate gene studies. The dimensional …

DRD4 gene and obsessive compulsive disorder: Do symptom dimensions have specific genetic correlates?

B Viswanath, M Purushottam, T Kandavel… - Progress in Neuro …, 2013 - Elsevier
INTRODUCTION: The dopamine D4 receptor (DRD4) is a promising candidate gene in
obsessive compulsive disorder (OCD). A 48-bp variable number of tandem repeats (VNTR) …