Neuronal calcium sensor proteins: generating diversity in neuronal Ca2+ signalling

RD Burgoyne - Nature Reviews Neuroscience, 2007 - nature.com
In neurons, intracellular calcium signals have crucial roles in activating neurotransmitter
release and in triggering alterations in neuronal function. Calmodulin has been widely …

Localization and targeting of voltage-dependent ion channels in mammalian central neurons

H Vacher, DP Mohapatra… - Physiological …, 2008 - journals.physiology.org
The intrinsic electrical properties and the synaptic input-output relationships of neurons are
governed by the action of voltage-dependent ion channels. The localization of specific …

The distribution and targeting of neuronal voltage-gated ion channels

HC Lai, LY Jan - Nature Reviews Neuroscience, 2006 - nature.com
Voltage-gated ion channels have to be at the right place in the right number to endow
individual neurons with their specific character. Their biophysical properties together with …

Localization of voltage-gated ion channels in mammalian brain

JS Trimmer, KJ Rhodes - Annu. Rev. Physiol., 2004 - annualreviews.org
▪ Abstract The intrinsic electrical properties of neurons are shaped in large part by the action
of voltage-gated ion channels. Molecular cloning studies have revealed a large family of ion …

Ancillary Subunits Associated With Voltage-Dependent K+ Channels

O Pongs, JR Schwarz - Physiological reviews, 2010 - journals.physiology.org
Since the first discovery of Kvβ-subunits more than 15 years ago, many more ancillary Kv
channel subunits were characterized, for example, KChIPs, KCNEs, and BKβ-subunits. The …

Calcium-dependent modulation and plasma membrane targeting of the AKT2 potassium channel by the CBL4/CIPK6 calcium sensor/protein kinase complex

K Held, F Pascaud, C Eckert, P Gajdanowicz… - Cell research, 2011 - nature.com
Potassium (K+) channel function is fundamental to many physiological processes. However,
components and mechanisms regulating the activity of plant K+ channels remain poorly …

Specific pattern of ionic channel gene expression associated with pacemaker activity in the mouse heart

C Marionneau, B Couette, J Liu, H Li… - The Journal of …, 2005 - Wiley Online Library
Even though sequencing of the mammalian genome has led to the discovery of a large
number of ionic channel genes, identification of the molecular determinants of cellular …

Structure and function of Kv4-family transient potassium channels

SG Birnbaum, AW Varga, LL Yuan… - Physiological …, 2004 - journals.physiology.org
Shal-type (Kv4. x) K+ channels are expressed in a variety of tissue, with particularly high
levels in the brain and heart. These channels are the primary subunits that contribute to …

Molecular physiology and modulation of somatodendritic A-type potassium channels

HH Jerng, PJ Pfaffinger, M Covarrubias - Molecular and Cellular …, 2004 - Elsevier
The somatodendritic subthreshold A-type K+ current (ISA) in nerve cells is a critical
component of the ensemble of voltage-gated ionic currents that determine somatodendritic …

Kv4 potassium channel subunits control action potential repolarization and frequency‐dependent broadening in rat hippocampal CA1 pyramidal neurones

J Kim, DS Wei, DA Hoffman - The Journal of physiology, 2005 - Wiley Online Library
A‐type potassium channels regulate neuronal firing frequency and the back‐propagation of
action potentials (APs) into dendrites of hippocampal CA1 pyramidal neurones. Recent …