Fluoroquinolones are synthetic antibacterial agents that stabilize the ternary complex of
prokaryotic topoisomerase II enzymes (gyrase and Topo IV), leading to extensive DNA …

Quinolones are among the most common frameworks present in the bioactive molecules
and hence represent an attractive starting point for the design of combinatorial libraries …

Abstract Background/Aim SARS‐CoV‐2 is one of the coronavirus families that emerged at
the end of 2019. It infected the respiratory system and caused a pandemic worldwide …

Palladium-Catalyzed Tandem Amination Reaction for the Synthesis of 4-Quinolones | Organic
Letters ACS ACS Publications C&EN CAS Find my institution Log In Organic Letters ACS …

The cycloacylation of aniline derivatives to 4-quinolones in the presence of Eaton's reagent
is described. This high-yielding methodology is applicable to a wide variety of functionalized …

In this work, a new series of arysulfonylhydrazine-1H-1, 2, 3-triazole derivatives were
synthesized, and their ability to inhibit the in vitro replication of HSV-1 was evaluated …

The synthesis of new 4-(phenylamino)-1-phenyl-1 H-pyrazolo [3, 4-b] pyridine-4-carboxylic
acid (3a-l) derivatives and the new 4-[(methylpyridin-2-yl) amino]-1-phenyl-1 H-pyrazolo [3 …

This review aims to provide a comprehensive report on the quinoline ring with respect to its
synthesis, reactivity, and therapeutic values. The reactivity of quinoline for the metal …

We report Rh (III)-catalyzed [3+ 3] annulation reactions for the preparation of functionalized 4-
quinolones from N-nitrosoanilines and cyclopropenones. This reaction allows C–C bond …

A copper‐catalyzed three‐component synthetic method has been developed for the
synthesis of substituted 4‐quinolone derivatives from substituted 3‐(2‐halophenyl)‐3 …