Recent advances in microscale electroporation

SE Choi, H Khoo, SC Hur - Chemical reviews, 2022 - ACS Publications
Electroporation (EP) is a commonly used strategy to increase cell permeability for
intracellular cargo delivery or irreversible cell membrane disruption using electric fields. In …

A comprehensive review on intracellular delivery

D Morshedi Rad, M Alsadat Rad… - Advanced …, 2021 - Wiley Online Library
Intracellular delivery is considered an indispensable process for various studies, ranging
from medical applications (cell‐based therapy) to fundamental (genome‐editing) and …

High throughput and highly controllable methods for in vitro intracellular delivery

J Brooks, G Minnick, P Mukherjee, A Jaberi, L Chang… - Small, 2020 - Wiley Online Library
In vitro and ex vivo intracellular delivery methods hold the key for releasing the full potential
of tissue engineering, drug development, and many other applications. In recent years, there …

Molecular beacon nano-sensors for probing living cancer cells

T Kuang, L Chang, X Peng, X Hu… - Trends in …, 2017 - cell.com
Heterogeneities and oncogenesis essentially result from proteomic disorders orchestrated
by changes in DNA and/or cytoplasmic mRNA. These genetic fluctuations, however, cannot …

Microfluidic device for stem cell differentiation and localized electroporation of postmitotic neurons

W Kang, JP Giraldo-Vela, SSP Nathamgari, T McGuire… - Lab on a Chip, 2014 - pubs.rsc.org
New techniques to deliver nucleic acids and other molecules for gene editing and gene
expression profiling, which can be performed with minimal perturbation to cell growth or …

Micro-and nanoscale technologies for delivery into adherent cells

W Kang, RL McNaughton, HD Espinosa - Trends in biotechnology, 2016 - cell.com
Several recent micro-and nanotechnologies have provided novel methods for biological
studies of adherent cells because the small features of these new biotools provide unique …

Single‐Cell Detection of mRNA Expression Using Nanofountain‐Probe Electroporated Molecular Beacons

JP Giraldo‐Vela, W Kang, RL McNaughton, X Zhang… - Small, 2015 - Wiley Online Library
New techniques for single‐cell analysis enable new discoveries in gene expression and
systems biology. Time‐dependent measurements on individual cells are necessary, yet the …

[HTML][HTML] Scanning probe microscope-based fluid dispensing

MK Ghatkesar, HH Perez Garza, F Heuck, U Staufer - Micromachines, 2014 - mdpi.com
Advances in micro and nano fabrication technologies have enabled fabrication of smaller
and more sensitive devices for applications not only in solid-state physics but also in …

“Writing biochips”: high-resolution droplet-to-droplet manufacturing of analytical platforms

G Arrabito, D Gulli, C Alfano, B Pignataro - Analyst, 2022 - pubs.rsc.org
The development of high-resolution molecular printing allows the engineering of analytical
platforms enabling applications at the interface between chemistry and biology, ie in …

Controlled molecular assembly via dynamic confinement of solvent

J Zhang, VA Piunova, Y Liu, A Tek… - The journal of …, 2018 - ACS Publications
Assembly from ultrasmall solution droplets follows a different dynamic from that of larger
scales. Using an independently controlled microfluidic probe in an atomic force microscope …