Immuno-positron emission tomography (immunoPET) is a paradigm-shifting molecular
imaging modality combining the superior targeting specificity of monoclonal antibody (mAb) …

Molecular imaging using radioisotope-or fluorophore-labeled antibodies is increasingly
becoming a critical component of modern precision medicine. Yet despite this promise, the …

Abstract Development of biomarkers that detect early stage resectable premalignant lesions
of colon can provide critical aid in the prevention of colorectal cancer. Recent lines of …

Safe and effective vectors play an important role in nucleic acid delivery processes. Ring-
opening reactions are quite often used to produce biomaterials with various functions and …

Near-infrared (NIR) fluorescence imaging is a promising new medical imaging modality.
Associated with a targeting molecule, NIR fluorophores can accumulate selectively in …

Heterodimerization of EGFR with HER2 coexpressed in breast cancer (BC) promotes tumor
growth, and increased EGFR expression is associated with trastuzumab resistance. Our aim …

The efficacy of external beam radiotherapy (EBRT) is dose dependent, but the dose that can
be applied to solid tumour lesions is limited by the sensitivity of the surrounding tissue. The …

Purpose Optical surgical navigation (OSN) will be a potent tool to help surgeons more
accurately and efficiently remove tumors. The purpose of this study was to evaluate a novel …

Galectins are carbohydrate binding proteins that function in many key cellular processes.
We have previously demonstrated that galectins are essential for tumor angiogenesis and …

The authors propose a concept of “systems engineering,” the approach to assessing the
extent of diseased tissue (EODT) in solid tumors. We modeled the proof of this concept …