Highlights•Cell autonomous polarity, its transmission through division, are unifying themes
for centrosome/primary cilium functions.•Adhesion-dependent acto-myosin fibers play a …

During neocortical development, many neuronally differentiating cells (neurons and
intermediate progenitor cells) are generated at the apical/ventricular surface by the division …

Stem cells are at the source of creating cellular diversity. Multiple mechanisms, including
basic cell biological processes, regulate their fate. The centrosome is at the core of many …

The centrosome is a tiny cytoplasmic organelle that organizes and constructs massive
molecular machines to coordinate diverse cellular processes. Due to its many roles during …

Axon formation critically relies on local microtubule remodeling and marks the first step in
establishing neuronal polarity. However, the function of the microtubule‐organizing …

Primary cilia are antenna-like organelles emanating from the cell surface. They are involved
in cell-to-cell communication and bidirectional signal transduction to/from the extracellular …

This review summarizes information about the specific features that are characteristic of the
centrosome and its relationship with the cell function of highly specialized cells, such as …

Centrosomes are best known as the microtubule organizing centers (MTOCs) of eukaryotic
cells. In addition to their classic role in chromosome segregation, centrosomes play diverse …

Neurons are highly polarized cells requiring precise regulation of trafficking and targeting of
membrane proteins to generate and maintain different and specialized compartments, such …

The protein connector enhancer of kinase suppressor of Ras 2 (CNKSR2), present in both
the postsynaptic density and cytoplasm of neurons, is a scaffolding protein with several …