Engineered living materials for sustainability

B An, Y Wang, Y Huang, X Wang, Y Liu, D Xun… - Chemical …, 2022 - ACS Publications
Recent advances in synthetic biology and materials science have given rise to a new form of
materials, namely engineered living materials (ELMs), which are composed of living matter …

Engineered hydrogels for mechanobiology

U Blache, EM Ford, B Ha, L Rijns… - Nature Reviews …, 2022 - nature.com
Cells' local mechanical environment can be as important in guiding cellular responses as
many well-characterized biochemical cues. Hydrogels that mimic the native extracellular …

Engineered living hydrogels

X Liu, ME Inda, Y Lai, TK Lu, X Zhao - Advanced Materials, 2022 - Wiley Online Library
Living biological systems, ranging from single cells to whole organisms, can sense, process
information, and actuate in response to changing environmental conditions. Inspired by …

Boosting checkpoint immunotherapy with biomaterials

L Liu, Y Pan, C Zhao, P Huang, X Chen, L Rao - ACS nano, 2023 - ACS Publications
The immune checkpoint blockade (ICB) therapy has revolutionized the field of cancer
treatment, while low response rates and systemic toxicity limit its clinical outcomes. With the …

Developing biomedical engineering technologies for reproductive medicine

Y Zhu, B Kong, R Liu, Y Zhao - Smart Medicine, 2022 - Wiley Online Library
Infertility is a rising global health issue with a far‐reaching impact on the socioeconomic
livelihoods. As there are highly complex causes of male and female infertility, it is highly …

Design, characterization and applications of nanocolloidal hydrogels

SM Morozova, A Gevorkian… - Chemical Society Reviews, 2023 - pubs.rsc.org
Nanocolloidal gels (NCGs) are an emerging class of soft matter, in which nanoparticles act
as building blocks of the colloidal network. Chemical or physical crosslinking enables NCG …

Novel nano-encapsulated probiotic agents: Encapsulate materials, delivery, and encapsulation systems

C Xu, Q Ban, W Wang, J Hou, Z Jiang - Journal of Controlled Release, 2022 - Elsevier
Gut microbes are closely associated with most human health. When ingested orally,
probiotics can effectively regulate the composition and quantity of human intestinal …

Biomaterials releasing drug responsively to promote wound healing via regulation of pathological microenvironment

H Li, B Li, D Lv, W Li, Y Lu, G Luo - Advanced Drug Delivery Reviews, 2023 - Elsevier
Wound healing is characterized by complex, orchestrated, spatiotemporal dynamic
processes. Recent findings demonstrated suitable local microenvironments were …

[HTML][HTML] Bacterial extracellular vesicles as bioactive nanocarriers for drug delivery: Advances and perspectives

H Liu, Q Zhang, S Wang, W Weng, Y Jing, J Su - Bioactive Materials, 2022 - Elsevier
Nanosized extracellular vesicles derived from bacteria contain diverse cargo and transfer
intercellular bioactive molecules to cells. Due to their favorable intercellular interactions, cell …

Synthetic protein condensates for cellular and metabolic engineering

ZG Qian, SC Huang, XX Xia - Nature chemical biology, 2022 - nature.com
Protein condensates are distinct structures assembled in living cells that concentrate
molecules via phase separation in a confined subcellular compartment. In the past decade …