Glycan-mediated molecular interactions in bacterial pathogenesis

S Lee, S Inzerillo, GY Lee, EM Bosire, SK Mahato… - Trends in …, 2022 - cell.com
Glycans are expressed on the surface of nearly all host and bacterial cells. Not surprisingly,
glycan-mediated molecular interactions play a vital role in bacterial pathogenesis and host …

Airway metabolic profiling during Streptococcus pneumoniae infection identifies branched chain amino acids as signatures of upper airway colonisation

AE Green, S Pottenger, MS Monshi, TE Barton… - PLoS …, 2023 - journals.plos.org
Streptococcus pneumoniae is a leading cause of community-acquired pneumonia and
bacteraemia and is capable of remarkable phenotypic plasticity, responding rapidly to …

A comprehensive analysis of pneumococcal two-component system regulatory networks

JS Pettersen, FD Nielsen… - NAR Genomics and …, 2024 - academic.oup.com
Two-component systems are key signal-transduction systems that enable bacteria to
respond to a wide variety of environmental stimuli. The human pathogen, Streptococcus …

Carbon source–dependent capsule thickness regulation in Streptococcus pneumoniae

JP Werren, N Mostacci, I Gjuroski… - Frontiers in cellular …, 2023 - frontiersin.org
Background The polysaccharide capsule of Streptococcus pneumoniae plays a major role in
virulence, adherence to epithelial cells, and overall survival of the bacterium in the human …

Pivotal Roles for Ribonucleases in Streptococcus pneumoniae Pathogenesis

D Sinha, JP Frick, K Clemons, ME Winkler, NR De Lay - Mbio, 2021 - Am Soc Microbiol
RNases perform indispensable functions in regulating gene expression in many bacterial
pathogens by processing and/or degrading RNAs. Despite the pivotal role of RNases in …

The two-component system YesMN promotes pneumococcal host-to-host transmission and regulates genes involved in zinc homeostasis

MA Zafar, A Costa-Terryl, TM Young - Infection and Immunity, 2023 - Am Soc Microbiol
The ability to sense and respond rapidly to the dynamic environment of the upper respiratory
tract (URT) makes Streptococcus pneumoniae (Spn) a highly successful human pathogen …

Molecular mechanisms of complex-type N-glycan breakdown and metabolism by the human intestinal bacterium Barnesiella intestinihominis

K Doi, K Mori, M Komatsu, A Shinoda, K Tashiro… - Journal of Bioscience …, 2025 - Elsevier
Intestinal bacteria play a crucial role in human health, for example, by maintaining immune
and metabolic homeostasis and protecting against pathogens. Survival in the human …

Host-intestinal microbiota interactions in Edwardsiella piscicida-induced lethal enteritis in big-belly seahorses: Novel insights into the role of Carbohydrate-Active …

L Jia, L Zhang, H Yang, L Li, S Zheng, Y Ma… - Fish & Shellfish …, 2025 - Elsevier
Edwardsiella piscicida-induced lethal enteritis is a major threat to the sustainable
development of seahorse aquaculture. The roles of Carbohydrate-Active enzymes …

Carbon catabolite repression on the Rgg2/3 quorum sensing system in Streptococcus pyogenes is mediated by PTSMan and Mga

JKK Woo, KS McIver, MJ Federle - Molecular microbiology, 2022 - Wiley Online Library
Streptococcus pyogenes, also known as group A Streptococcus or GAS, is a human‐
restricted pathogen causing a diverse array of infections. The ability to adapt to different …

Role of EmaSR in Ethanol Metabolism by Acinetobacter baumannii

HY Shu, YW Huang, PY Tsai, KS Hsieh… - International Journal of …, 2022 - mdpi.com
Acinetobacter baumannii is a well-known nosocomial pathogen that can survive in different
environments through the use of intricate networks to regulate gene expression. Two …