The biology and life-cycle of human papillomaviruses
Human papillomaviruses (HPVs) comprise a diverse group, and have different epithelial
tropisms and life-cycle strategies. Many HPVs are classified as low-risk, as they are only …
tropisms and life-cycle strategies. Many HPVs are classified as low-risk, as they are only …
Head and neck cancer
Most head and neck cancers are squamous cell carcinomas that develop in the upper
aerodigestive epithelium after exposure to carcinogens such as tobacco and alcohol …
aerodigestive epithelium after exposure to carcinogens such as tobacco and alcohol …
Neoadjuvant immunotherapy with nivolumab and ipilimumab induces major pathological responses in patients with head and neck squamous cell carcinoma
JL Vos, JBW Elbers, O Krijgsman, JJH Traets… - Nature …, 2021 - nature.com
Surgery for locoregionally advanced head and neck squamous cell carcinoma (HNSCC)
results in 30‒50% five-year overall survival. In IMCISION (NCT03003637), a non …
results in 30‒50% five-year overall survival. In IMCISION (NCT03003637), a non …
Human papillomavirus testing in head and neck carcinomas: guideline from the College of American Pathologists
Context Human papillomavirus (HPV) is a major cause of oropharyngeal squamous cell
carcinomas, and HPV (and/or surrogate marker p16) status has emerged as a prognostic …
carcinomas, and HPV (and/or surrogate marker p16) status has emerged as a prognostic …
[HTML][HTML] Neoadjuvant nivolumab for patients with resectable HPV-positive and HPV-negative squamous cell carcinomas of the head and neck in the CheckMate 358 …
Background Head and neck squamous cell carcinomas (HNSCCs) are common
malignancies caused by carcinogens, including tobacco and alcohol, or infection with …
malignancies caused by carcinogens, including tobacco and alcohol, or infection with …
Human papillomavirus and rising oropharyngeal cancer incidence in the United States
AK Chaturvedi, EA Engels, RM Pfeiffer… - Journal of clinical …, 2011 - ascopubs.org
Purpose Recent increases in incidence and survival of oropharyngeal cancers in the United
States have been attributed to human papillomavirus (HPV) infection, but empirical evidence …
States have been attributed to human papillomavirus (HPV) infection, but empirical evidence …
Human papillomavirus and survival of patients with oropharyngeal cancer
Background Oropharyngeal squamous-cell carcinomas caused by human papillomavirus
(HPV) are associated with favorable survival, but the independent prognostic significance of …
(HPV) are associated with favorable survival, but the independent prognostic significance of …
[HTML][HTML] Guidelines for prevention and treatment of opportunistic infections in HIV-infected adults and adolescents
This report updates and combines earlier versions of guidelines for the prevention and
treatment of opportunistic infections (OIs) in HIV-infected adults (ie, persons aged> 18 years) …
treatment of opportunistic infections (OIs) in HIV-infected adults (ie, persons aged> 18 years) …
Improved survival of patients with human papillomavirus–positive head and neck squamous cell carcinoma in a prospective clinical trial
Background The improved prognosis for patients with human papillomavirus (HPV)–positive
head and neck squamous cell carcinoma (HNSCC) relative to HPV-negative HNSCC …
head and neck squamous cell carcinoma (HNSCC) relative to HPV-negative HNSCC …
Tumour-infiltrating lymphocytes predict for outcome in HPV-positive oropharyngeal cancer
MJ Ward, SM Thirdborough, T Mellows, C Riley… - British journal of …, 2014 - nature.com
Background: Human papillomavirus (HPV)-positive oropharyngeal cancer (OPSCC) is
associated with improved survival compared with HPV-negative disease. However, a …
associated with improved survival compared with HPV-negative disease. However, a …