HIV DNA sequencing to detect archived antiretroviral drug resistance
Abstract Introduction Proviral HIV DNA integrated within CD4 T-cells maintains an archive of
viral variants that replicate during the course of the infection, including variants with reduced …
viral variants that replicate during the course of the infection, including variants with reduced …
Dolutegravir-based regimen ensures high virological success despite prior exposure to efavirenz-based first-line ART in Cameroon: an evidence of a successful …
ENJ Semengue, J Fokam, NK Etame, E Molimbou… - Viruses, 2022 - mdpi.com
To ensure optimal prescribing practices in the dolutegravir-era in Cameroon, we compared
first-line virological response (VR) under tenofovir+ lamivudine+ dolutegravir (TLD) …
first-line virological response (VR) under tenofovir+ lamivudine+ dolutegravir (TLD) …
[HTML][HTML] Realizing the promise of dolutegravir in effectively treating children and adolescents living with HIV in real-world settings in 6 countries in Eastern and …
JM Bacha, S Dlamini, F Anabwani… - The Pediatric …, 2023 - journals.lww.com
Background: Despite encouraging results from clinical trials and in high-income countries,
large-scale data on the effectiveness and safety of dolutegravir (DTG) in children and …
large-scale data on the effectiveness and safety of dolutegravir (DTG) in children and …
Low prevalence of pre-treatment and acquired drug resistance to Dolutegravir among treatment naive individuals initiating on Tenofovir, lamivudine and Dolutegravir …
Dolutegravir (DTG) use in combination with tenofovir and lamivudine (TLD) is scaling up in
Africa. However, HIV drug resistance (HIVDR) data to DTG remain scarce in Zimbabwe. We …
Africa. However, HIV drug resistance (HIVDR) data to DTG remain scarce in Zimbabwe. We …
High-level resistance to non-nucleos (t) ide reverse transcriptase inhibitor based first-line antiretroviral therapy in Ghana; A 2017 study
PK Parbie, CZY Abana, D Kushitor… - Frontiers in …, 2022 - frontiersin.org
Expanding access to effective antiretroviral therapy (ART) is a major tool for management of
Human Immunodeficiency Virus (HIV) infection. However, rising levels of HIV drug …
Human Immunodeficiency Virus (HIV) infection. However, rising levels of HIV drug …
HIV-1 drug resistance and genetic diversity in a cohort of people with HIV-1 in Nigeria
Objective: This study was designed to provide information on the genetic diversity of HIV-1
and drug resistance mutations in Nigeria, as there is limited understanding of variants …
and drug resistance mutations in Nigeria, as there is limited understanding of variants …
Drug resistance to integrase strand-transfer inhibitors among HIV-1-infected adults in Guangdong, China
Y Lan, L Li, R Xin, X Ling, X Deng, J Li, L Li, W Cai, F Li… - Pathogens, 2022 - mdpi.com
Background: Integrase strand-transfer inhibitor (INSTI)-containing regimens have gradually
been administered in Guangdong Province, China beginning in 2016, and INSTI-related …
been administered in Guangdong Province, China beginning in 2016, and INSTI-related …
Virologic outcomes of switching to dolutegravir functional mono-or dual therapy with a non-cytosine nucleoside analog: a retrospective study of treatment-experienced …
CP Rolle, V Nguyen, F Hinestrosa… - AIDS Research and …, 2021 - Springer
Background Dolutegravir (DTG) monotherapy results in virologic failure and the
development of DTG resistance. Here, we evaluated virologic outcomes of patients switched …
development of DTG resistance. Here, we evaluated virologic outcomes of patients switched …
Time to Immunologic Recovery and Its Determinant Factors Among Adult HIV Patients Who Initiated Antiretroviral Treatment at Hiwot Fana Specialized University …
F Demeke Bayou, S Nigussie Amare - HIV/AIDS-Research and …, 2021 - Taylor & Francis
Objective To determine the time to immunologic recovery and its determinant factors among
adult HIV patients who initiated antiretroviral treatment at Hiwot Fana Specialized University …
adult HIV patients who initiated antiretroviral treatment at Hiwot Fana Specialized University …
Virological, weight, and drug resistance outcomes among patients initiating a dolutegravir-based first line ART regimen in Zimbabwe
V Kouamou, T Washaya, T Mapangisana, CE Ndhlovu… - AIDS, 2022 - journals.lww.com
Objective: Dolutegravir (DTG)-based ART is being scaled up in Africa. However, clinical
experience with DTG and patterns of HIV drug resistance (HIVDR) are sparse in Zimbabwe …
experience with DTG and patterns of HIV drug resistance (HIVDR) are sparse in Zimbabwe …