Gadolinium-based contrast agent toxicity: a review of known and proposed mechanisms

M Rogosnitzky, S Branch - Biometals, 2016 - Springer
Gadolinium chelates are widely used as contrast media for magnetic resonance imaging.
The approved gadolinium-based contrast agents (GBCAs) have historically been …

Gadolinium: pharmacokinetics and toxicity in humans and laboratory animals following contrast agent administration

J Davies, P Siebenhandl-Wolff, F Tranquart… - Archives of …, 2022 - Springer
Gadolinium-based contrast agents (GBCAs) have transformed magnetic resonance imaging
(MRI) by facilitating the use of contrast-enhanced MRI to allow vital clinical diagnosis in a …

Gadolinium in medical imaging—usefulness, toxic reactions and possible countermeasures—A review

L Blomqvist, GF Nordberg, VM Nurchi, JO Aaseth - Biomolecules, 2022 - mdpi.com
Gadolinium (Gd) is one of the rare-earth elements. The properties of its trivalent cation
(Gd3+) make it suitable to serve as the central ion in chelates administered intravenously to …

Novel 2-Substituted 3-Hydroxy-1,6-dimethylpyridin-4(1H)-ones as Dual-Acting Biofilm Inhibitors of Pseudomonas aeruginosa

J Liu, JS Hou, YB Li, ZY Miao, PH Sun… - Journal of Medicinal …, 2020 - ACS Publications
2-Heptyl-3-hydroxy-4 (1 H)-quinolone (PQS), a compound from P. aeruginosa, functions as
both a quorum sensing (QS) regulator and a potent iron chelator to induce expression of …

Coordination chemistry of f-block metal ions with ligands bearing bio-relevant functional groups

L Götzke, G Schaper, J März, P Kaden… - Coordination Chemistry …, 2019 - Elsevier
Over recent decades there has been a great deal of interest and associated research into
aspects of the f-block (lanthanide and actinide) metal chemistry of naturally-occurring …

Gadolinium-based contrast agents–what is the evidence for 'gadolinium deposition disease'and the use of chelation therapy?

KA Layne, DM Wood, PI Dargan - Clinical Toxicology, 2020 - Taylor & Francis
Introduction: Gadolinium-based contrast agents are widely used for magnetic resonance
imaging and, until recently, had been generally considered to have an excellent safety …

Chemical insights into the issues of Gd retention in the brain and other tissues upon the administration of Gd‐containing MRI contrast agents

E Gianolio, ED Gregorio, S Aime - European Journal of …, 2019 - Wiley Online Library
Gadolinium bearing contrast agents (GBCA) are commonly used in clinical settings as they
add relevant physiological information to the superb anatomical resolution of the MR …

Toxicity Mechanisms of Gadolinium and Gadolinium-Based Contrast Agents—A Review

S Coimbra, S Rocha, NR Sousa, C Catarino… - International Journal of …, 2024 - mdpi.com
Gadolinium-based contrast agents (GBCAs) have been used for more than 30 years to
improve magnetic resonance imaging, a crucial tool for medical diagnosis and treatment …

Gadolinium toxicity: iron and ferroportin as central targets

S Swaminathan - Magnetic resonance imaging, 2016 - Elsevier
Gadolinium-based magnetic resonance (MR) contrast agents (GBCM) causes a devastating
systemic fibrosing illness, nephrogenic systemic fibrosis (NSF), in patients with reduced …

Microextraction of Gadolinium MRI contrast agent using core-shell Fe3O4@ SiO2 nanoparticles: optimization of adsorption conditions and in-vitro study

M Naghizadeh, MA Taher, AM Tamaddon… - Environmental …, 2019 - Elsevier
Fe 3 O 4 nanoparticles have been explored as highly efficient materials for heavy metal ion
removal by adsorption process. In this contribution, a novel core–shell Fe 3 O 4@ SiO 2 …