Smart nanomaterials in cancer theranostics: challenges and opportunities

BK Kashyap, VV Singh, MK Solanki, A Kumar… - ACS …, 2023 - ACS Publications
Cancer is ranked as the second leading cause of death globally. Traditional cancer
therapies including chemotherapy are flawed, with off-target and on-target toxicities on the …

Lactoferrin, a multi-functional glycoprotein: Active therapeutic, drug nanocarrier & targeting ligand

AO Elzoghby, MA Abdelmoneem, IA Hassanin… - Biomaterials, 2020 - Elsevier
Recent progress in protein-based nanomedicine, inspired by the success of Abraxane®
albumin-paclitaxel nanoparticles, have resulted in novel therapeutics used for treatment of …

[HTML][HTML] Holo-lactoferrin: the link between ferroptosis and radiotherapy in triple-negative breast cancer

Z Zhang, M Lu, C Chen, X Tong, Y Li, K Yang, H Lv… - Theranostics, 2021 - ncbi.nlm.nih.gov
Abstract Rationale: Iron-saturated Lf (Holo-Lactoferrin, Holo-Lf) exhibits a superior
anticancer property than low iron-saturated Lf (Apo-Lf). Ferroptosis is an iron-dependent cell …

[HTML][HTML] Combined chemotherapy with cyclooxygenase-2 (COX-2) inhibitors in treating human cancers: Recent advancement

S Li, M Jiang, L Wang, S Yu - Biomedicine & Pharmacotherapy, 2020 - Elsevier
Chemotherapy with a single chemotherapeutic agent or a combined chemotherapeutic
regimen is the clinically standardized treatment for almost all human cancers. Upregulated …

Synthesis of lactoferrin mesoporous silica nanoparticles for pemetrexed/ellagic acid synergistic breast cancer therapy

OM Ali, AA Bekhit, SN Khattab, MW Helmy… - Colloids and Surfaces B …, 2020 - Elsevier
Despite the clinical approval of few nanomedicines for cancer therapy, some drawbacks still
impede their improved efficiency including low drug loading, off-target toxicity and …

Preclinical cancer theranostics—from nanomaterials to clinic: the missing link

KK Johnson, P Koshy, JL Yang… - Advanced Functional …, 2021 - Wiley Online Library
Nanomaterials with cancer‐imaging and therapeutic properties have emerged as the
principal focus of nanotheranostics. The past decade has experienced a significant increase …

Emerging nanopharmaceuticals and nanonutraceuticals in cancer management

L Salama, ER Pastor, T Stone, SA Mousa - Biomedicines, 2020 - mdpi.com
Nanotechnology is the science of nanoscale, which is the scale of nanometers or one
billionth of a meter. Nanotechnology encompasses a broad range of technologies, materials …

Active cellular and subcellular targeting of nanoparticles for drug delivery

OK Nag, JB Delehanty - Pharmaceutics, 2019 - mdpi.com
Nanoparticle (NP)-mediated drug delivery (NMDD) for active targeting of diseases is a
primary goal of nanomedicine. NPs have much to offer in overcoming the limitations of …

Recent progress in lipid nanoparticles for cancer theranostics: opportunity and challenges

SI Bukhari, SS Imam, MZ Ahmad, PR Vuddanda… - Pharmaceutics, 2021 - mdpi.com
Cancer is one of the major leading causes of mortality in the world. The implication of
nanotherapeutics in cancer has garnered splendid attention owing to their capability to …

Bioinspired quantum dots for cancer therapy: A mini-review

A Kumar, KRB Singh, MD Ghate, H Lalhlenmawia… - Materials Letters, 2022 - Elsevier
The global burden of cancer increases with the passing year and is becoming the primary
cause of death globally. Chemotherapy plays an important role but produces side effects …