Vitamin C and the lens: new insights into delaying the onset of cataract

JC Lim, M Caballero Arredondo, AJ Braakhuis… - Nutrients, 2020 - mdpi.com
Cataracts or clouding of the lens is the leading cause of blindness in the world. Age and
diabetes are major risk factors, and with an increasing aging and diabetic population, the …

Reported evidence of vitamin E protection against cataract and glaucoma

M Tanito - Free Radical Biology and Medicine, 2021 - Elsevier
Cataract and glaucoma are the major causes of severe visual loss and blindness in older
adults. This review article describes the currently available basic and clinical evidence …

[HTML][HTML] Age-related changes in eye lens biomechanics, morphology, refractive index and transparency

C Cheng, J Parreno, RB Nowak, SK Biswas… - Aging (Albany …, 2019 - ncbi.nlm.nih.gov
Life-long eye lens function requires an appropriate gradient refractive index, biomechanical
integrity and transparency. We conducted an extensive study of wild-type mouse lenses 1 …

[HTML][HTML] Changing Trends in the Global Burden of Cataract Over the Past 30 Years: Retrospective Data Analysis of the Global Burden of Disease Study 2019

B Jiang, T Wu, W Liu, G Liu, P Lu - JMIR Public Health and …, 2023 - publichealth.jmir.org
Background: Cataracts now account for the largest proportion of the global burden of
blindness and vision loss. Understanding the changing trends in the global burden of …

Roles of eph-ephrin signaling in the eye lens cataractogenesis, biomechanics, and homeostasis

S Murugan, C Cheng - Frontiers in Cell and Developmental Biology, 2022 - frontiersin.org
The eye lens is responsible for fine focusing of light onto the retina, and its function relies on
tissue transparency and biomechanical properties. Recent studies have demonstrated the …

Effect of berberine on glycation, aldose reductase activity, and oxidative stress in the lenses of streptozotocin-induced diabetic rats in vivo—a preliminary study

M Zych, W Wojnar, M Kielanowska… - International Journal of …, 2020 - mdpi.com
Diabetes mellitus affects the eye lens, leading to cataract formation by glycation, osmotic
stress, and oxidative stress. Berberine, an isoquinoline alkaloid, is a natural compound that …

[HTML][HTML] Traditional and dairy products and vegetables dietary patterns are inversely associated with the risk of cataract in the Middle age and aged population: a case …

S Amini, S Jafarirad, B Abiri, P Delgarm… - The Journal of nutrition …, 2021 - Elsevier
Objectives Cataract is one of the most common causes of visual impairment and blindness
in the world. In the present study, we have been trying to investigate the relationship …

[HTML][HTML] The Association between dietary vitamin A and C intakes and cataract: Data from Korea National Health and Nutrition Examination Survey 2012

JH Choi, E Lee, YR Heo - Clinical Nutrition Research, 2020 - ncbi.nlm.nih.gov
Oxidative stress in eye lens is one of the main causes of the cataract. Dietary antioxidants
including vitamin A and C are therefore known to be associated with the risk of the disease …

Fruit and vegetable intake and the risk of cataract: Insights from the UK Biobank study

H Fan, X Han, X Shang, Z Zhu, M He, G Xu, Z Chen… - Eye, 2023 - nature.com
Purpose: A prospective cohort study to investigate the association between fruit and
vegetable (F&V) intake and the risk of cataract. Methods: We included 72,160 participants …

Intraocular calcidiol: Uncovering a role for vitamin D in the eye

J Rullo, T Pennimpede, PM Far, YN Strube… - The Journal of Steroid …, 2020 - Elsevier
Vitamin D has emerged as a potentially important molecule in ophthalmology. To date, all
ophthalmic data pertaining to vitamin D has been restricted primarily to tear and serum …