DNA nanotechnology has now enabled the self-assembly of almost any prescribed 3-
dimensional nanoscale structure in large numbers and with high fidelity. These structures …

DNA molecules that store genetic information in living creatures can be repurposed as
building blocks to construct artificial architectures, ranging from the nanoscale to the …

Multivalent presentation of ligands often enhances receptor activation and downstream
signalling. DNA origami offers a precise nanoscale spacing of ligands, a potentially useful …

Three-dimensional wireframe DNA origami have programmable structural and sequence
features that render them potentially suitable for prophylactic and therapeutic applications …

Targeted chemo-phototherapy has received widespread attention in cancer treatment for its
advantages in reducing the side effects of chemotherapeutics and improving therapeutic …

Protein-based virus-like particles (P-VLPs) are commonly used to spatially organize
antigens and enhance humoral immunity through multivalent antigen display. However, P …

Effective and safe vaccines are invaluable tools in the arsenal to fight infectious diseases.
The rapid spreading of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …

The past few decades have witnessed the evolving paradigm for cancer therapy from
nonspecific cytotoxic agents to selective, mechanism‐based therapeutics, especially …

Wireframe DNA origami can be used to fabricate virus-like particles for a range of
biomedical applications, including the delivery of nucleic acid therapeutics. However, the …

Biocompatible DNA origami nanostructures (DONs) attract significant interest as potential
targeted drug carriers. Their sensitivity to various environmental triggers is beneficial as a …