Background In the 5 years that have passed since the publication of the 2018 International
Consensus Statement on Allergy and Rhinology: Allergic Rhinitis (ICAR‐Allergic Rhinitis …

I. Executive Summary Background The 5 years since the publication of the first International
Consensus Statement on Allergy and Rhinology: Rhinosinusitis (ICAR‐RS) has witnessed …

Background Critical examination of the quality and validity of available allergic rhinitis (AR)
literature is necessary to improve understanding and to appropriately translate this …

Barrier tissue dysfunction is a fundamental feature of chronic human inflammatory diseases
1. Specialized subsets of epithelial cells—including secretory and ciliated cells …

This comprehensive practice parameter for allergic rhinitis (AR) and nonallergic rhinitis
(NAR) provides updated guidance on diagnosis, assessment, selection of monotherapy and …

Contributing Authors Isam Alobid, MD, PhD1, Nithin D. Adappa, MD2, Henry P. Barham,
MD3, Thiago Bezerra, MD4, Nadieska Caballero, MD5, Eugene G. Chang, MD6, Gaurav …

Knowledge of chronic rhinosinusitis (CRS) epidemiology may directly impact patient care:
aiding patient identification and establishing accurate diagnosis as well as informing …

Objective This update of a 2007 guideline from the American Academy of Otolaryngology—
Head and Neck Surgery Foundation provides evidence-based recommendations to manage …

Systemic type 2 inflammation encompassing T helper 2 (TH2)-type responses is emerging
as a unifying feature of both classically defined allergic diseases, such as asthma, and a …

Background To date, no study has evaluated the diversity of TH cell cytokine patterns of
patients with chronic rhinosinusitis (CRS) among centers in different continents using …