The complement cascade, traditionally considered an effector arm of innate immunity
required for host defense against pathogens, is now recognized as a crucial pathogenic …

Renal interstitial fibrosis: mechanisms and evaluation : Current Opinion in Nephrology and
Hypertension Renal interstitial fibrosis: mechanisms and evaluation : Current Opinion in …

Prospective studies of unselected indication biopsies from kidney transplants, combining
conventional assessment with molecular analysis, have created a new understanding of …

Long-term graft survival after kidney transplantation remains unsatisfactory and
unpredictable. Interstitial fibrosis and tubular atrophy are major contributors to late graft loss; …

Background The copy number of donor-derived cell-free DNA (dd-cfDNA) in blood
correlates with acute rejection (AR) in heart transplantation. We analyzed urinary dd-cfDNA …

The aberrant activation of complement system in several kidney diseases suggests that this
pillar of innate immunity has a critical role in the pathophysiology of renal damage of …

Renal transplant recipients who experience delayed graft function have increased risks of
rejection and long-term graft failure. Ischemic damage is the most common cause of delayed …

Genomics, proteomics and molecular biology lead to tremendous advances in all fields of
medical sciences. Among these the finding of biomarkers as non invasive indicators of …

Ever since the discovery of the major histocompatibility complex, scientific and clinical
understanding in the field of transplantation has been advanced through genetic and …

The degree of progressive chronic histological damage is associated with long-term renal
allograft survival. In order to identify promising molecular targets for timely intervention, we …