Long non-coding RNA in the pathogenesis of cancers

Y Chi, D Wang, J Wang, W Yu, J Yang - Cells, 2019 - mdpi.com
The incidence and mortality rate of cancer has been quickly increasing in the past decades.
At present, cancer has become the leading cause of death worldwide. Most of the cancers …

Biomarkers in colorectal cancer: current research and future prospects

OO Ogunwobi, F Mahmood, A Akingboye - International journal of …, 2020 - mdpi.com
Colorectal cancer (CRC) is a leading cause of death worldwide, despite progress made in
detection and management through surgery, chemotherapy, radiotherapy, and …

Unraveling the ncRNA landscape that governs colorectal cancer: A roadmap to personalized therapeutics

NM Hamdy, MB Zaki, NI Rizk, NM Abdelmaksoud… - Life Sciences, 2024 - Elsevier
Colorectal cancer (CRC) being one of the most common malignancies, has a significant
death rate, especially when detected at an advanced stage. In most cases, the fundamental …

[HTML][HTML] The HOTTIP (HOXA transcript at the distal tip) lncRNA: Review of oncogenic roles in human

S Ghafouri-Fard, S Dashti, M Taheri - Biomedicine & Pharmacotherapy, 2020 - Elsevier
HOXA transcript at the distal tip (HOTTIP) is a 3764 nucleotide long non-coding RNA
(lncRNA) encoded from a genomic region in the 5′ tip of the HOXA locus. This lncRNA has …

PVT1 Long Non-coding RNA in Gastrointestinal Cancer

Á Martínez-Barriocanal, D Arango, H Dopeso - Frontiers in Oncology, 2020 - frontiersin.org
Whole genome and transcriptome sequencing technologies have led to the identification of
many long non-coding RNAs (lncRNAs) and stimulated the research of their role in health …

Mechanisms of long non‐coding RNA function in colorectal cancer tumorigenesis

A Poursheikhani, MR Abbaszadegan… - Asia‐Pacific Journal …, 2021 - Wiley Online Library
Colorectal cancer (CRC) is one of the most common cancers globally. Although a variety of
CRC screening methods have been developed, many patients are diagnosed at advanced …

Biomarkers (mRNAs and non-coding RNAs) for the diagnosis and prognosis of colorectal cancer–from the body fluid to tissue level

J He, F Wu, Z Han, M Hu, W Lin, Y Li, M Cao - Frontiers in oncology, 2021 - frontiersin.org
In recent years, the diagnosis and treatment of colorectal cancer (CRC) have been
continuously improved, but the mortality rate continues to be high, especially in advanced …

Identification of LncPVT1 and CircPVT1 as prognostic biomarkers in human colorectal polyps

M RezaSoltani, F Forouzesh, Z Salehi, MR Zabihi… - Scientific Reports, 2023 - nature.com
LncPVT1 and CircPVT1 are isoforms for the PVT1 gene and are associated with cancer
progression and carcinogenesis. Our study investigated the expression of LncPVT1 and …

Regulatory role of long non‑coding RNA UCA1 in signaling pathways and its clinical applications

Z Liu, Y Wang, S Yuan, F Wen, J Liu… - Oncology …, 2021 - spandidos-publications.com
Long non‑coding RNA metastasis‑associated urothelial carcinoma associated 1 (UCA1)
plays a pivotal role in various human diseases. Its gene expression is regulated by several …

Long noncoding RNA EPB41L4A‐AS1 functions as an oncogene by regulating the Rho/ROCK pathway in colorectal cancer

J Bin, S Nie, Z Tang, A Kang, Z Fu, Y Hu… - Journal of cellular …, 2021 - Wiley Online Library
Colorectal cancer (CRC) is one of the most common malignant tumors worldwide. In terms of
cancer‐related death, colon cancer ranks second and third among men and women …