Periodontitis is a chronic inflammatory condition that often causes serious damage to tooth-
supporting tissues. The limited successful outcomes of clinically available approaches …

Teeth are subject to a variety of mechanical forces and vectors. The periodontal ligament
(PDL), fibrous tissue that connects the cementum of the tooth to the bony socket, plays a …

Recent advances in 3D printing offer a prospective avenue for producing transplantable
human tissues with complex geometries; however, the appropriate 3D‐printed scaffolds …

The interface between soft and hard tissues is constituted by a gradient change of cell types
and matrix compositions that are optimally designed for proper load transmission and injury …

Stem cell/scaffold-based tissue engineering technology is expected to regenerate tooth root,
thus replace dental implant. Although numerous patterns of biological tooth root have been …

Periodontal ligament (PDL) is assembled from highly organized collagen fiber bundles (PDL
principal fibers) that are crucial in supporting teeth and buffering mechanical force …

Periodontal ligament (PDL) is mainly composed of collagen fiber bundles, and the content of
collagen fiber is an important factor affecting the mechanical properties of PDL. Based on …

Aim To date, controversies still exist regarding the exact cellular origin and regulatory
mechanisms of periodontium development, which hinders efforts to achieve ideal …

Engineering complete periodontal tissue regeneration remains a considerable clinical
challenge because the native periodontium is composed of hard mineralized and soft …

Herein, the recent advances in the development of resorbable polymeric‐based
biomaterials, their geometrical forms, resorption mechanisms, and their capabilities in …