[HTML][HTML] Anti-inflammatory, anti-oxidant, and immunomodulatory activities of the genus Ferula and their constituents: A review

Z Ghasemi, R Rezaee, MR Aslani… - Iranian journal of basic …, 2021 - ncbi.nlm.nih.gov
Ferula is a genus of the family Apiaceae and it includes around 170 species of flowering
plants mostly native to the Mediterranean region and eastern to central Asia. In Iran, Ferula …

Natural compounds regulate the PI3K/Akt/GSK3β pathway in myocardial ischemia-reperfusion injury

AH Ajzashokouhi, R Rezaee, N Omidkhoda, G Karimi - Cell Cycle, 2023 - Taylor & Francis
ABSTRACT The PI3K/Akt/GSK3β pathway is crucial in regulating cardiomyocyte growth and
survival. It has been shown that activation of this pathway alleviates the negative impact of …

Nrf2/ARE activators improve memory in aged mice via maintaining of mitochondrial quality control of brain and the modulation of gut microbiome

IS Sadovnikova, AP Gureev, DA Ignatyeva… - Pharmaceuticals, 2021 - mdpi.com
Aging is one of the most serious factors for central nervous dysfunctions, which lead to
cognitive impairment. New highly effective drugs are required to slow the development of …

A review on pain‐relieving activity of berberine

M Hashemzaei, R Rezaee - Phytotherapy Research, 2021 - Wiley Online Library
As isoquinoline alkaloid naturally occurs in Coptis and Berberis species, berberine (BER)
has shown anti‐oxidant, anti‐tumour, anti‐bacterial and hepatoprotective activities and …

Curculigoside rescues hippocampal synaptic deficits elicited by PTSD through activating cAMP‐PKA signaling

M Ji, Z Zhang, F Gao, S Yang, J Wang… - Phytotherapy …, 2023 - Wiley Online Library
Chronic traumatic stress results in various psychiatric disorders, especially posttraumatic
stress disorder (PTSD). Previous study demonstrated that curculigoside (CUR) a component …

Resveratrol protects BV2 mouse microglial cells against LPS-induced inflammatory injury by altering the miR-146a-5p/TRAF6/NF-κB axis

YT Ge, AQ Zhong, GF Xu, Y Lu - Immunopharmacology and …, 2019 - Taylor & Francis
Objective: To investigate the role of miR-146a-5p in the effects of resveratrol (RSV) on
inflammatory response in BV2 mouse microglial cells. Materials and methods: BV2 cells …

[HTML][HTML] Resveratrol, curcumin and gallic acid attenuate glyoxal-induced damage to rat renal cells

M Hashemzaei, K Tabrizian, Z Alizadeh… - Toxicology Reports, 2020 - Elsevier
Abstract Glyoxal (GO), a by-product of glucose auto-oxidation, is involved in the glycation of
proteins/lipids and formation of advanced glycation (AGE) and lipoxidation (ALE) end …

Morinda officinalis oligosaccharides ameliorate depressive‐like behaviors in poststroke rats through upregulating GLUT3 to improve synaptic activity

J Zhu, Q Peng, Y Xu, H Xu, Y Wan, Z Li… - The FASEB …, 2020 - Wiley Online Library
Poststroke depression (PSD) is one of the most common psychiatric diseases afflicting
stroke survivors, yet the underlying mechanism is poorly understood. The pathophysiology …

[HTML][HTML] Hormetic effects of curcumin on oxidative stress injury induced by trivalent arsenic in isolated rat hepatocytes

M Amirmostofian, F Akbari, M Hashemzaei… - Avicenna Journal of …, 2023 - ncbi.nlm.nih.gov
Objective: Arsenic (As) poisoning is a worldwide public health problem. Arsenic can cause
cancer, diabetes, hepatic problems, etc. Hence, we investigated possible hepatoprotective …

Effects of nano-curcumin on noise stress-induced hippocampus-dependent memory impairment: behavioral and electrophysiological aspects

A Alinaghipour, G Ashabi, E Riahi, M Soheili… - Pharmacological …, 2022 - Springer
Background Noise pollution is one of the fundamental factors in the etiology of many
disorders. Noise stress adversely affects cognitive behaviors and long-term potentiation …