Mortality in systemic lupus erythematosus: causes, predictors and interventions

V Ocampo-Piraquive, I Nieto-Aristizábal… - Expert review of …, 2018 - Taylor & Francis
Introduction: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease
characterized by organ damage, flare-remission pattern, and increased mortality when …

Mortality in systemic lupus erythematosus: an updated review

CE Fors Nieves, PM Izmirly - Current rheumatology reports, 2016 - Springer
Both systemic lupus erythematosus (SLE) and its treatments can contribute to increased
mortality rates. The focus of this review is recent studies on mortality and comorbidities …

KDIGO 2021 clinical practice guideline for the management of glomerular diseases

BH Rovin, SG Adler, J Barratt, F Bridoux… - Kidney …, 2021 - kidney-international.org
Glomerular disease, be it primary or secondary, occurring in the setting of systemic
autoimmune diseases, infections, drugs, or malignancy, affects individuals of all ages. In …

CD38 reduces mitochondrial fitness and cytotoxic T cell response against viral infection in lupus patients by suppressing mitophagy

PM Chen, E Katsuyama, A Satyam, H Li, J Rubio… - Science …, 2022 - science.org
Infection is one of the major causes of mortality in patients with systemic lupus
erythematosus (SLE). We previously found that CD38, an ectoenzyme that regulates the …

Humoral and cellular response to COVID-19 vaccination in patients with autoimmune inflammatory rheumatic diseases under real-life conditions

M Krasselt, U Wagner, P Nguyen, C Pietsch… - …, 2022 - academic.oup.com
Objectives Successful vaccination is key to overcoming the COVID-19 pandemic.
Immunosuppressive medication is known to potentially compromise vaccination responses …

The risk of infections in adult patients with systemic lupus erythematosus: systematic review and meta-analysis

JM Pego-Reigosa, L Nicholson, N Pooley… - …, 2021 - academic.oup.com
Objectives We conducted a systematic review and meta-analysis to determine the
magnitude of infection risk in patients with SLE and evaluate the effect of general and SLE …

Neurological immunotherapy in the era of COVID-19—looking for consensus in the literature

C Korsukewitz, SW Reddel, A Bar-Or… - Nature reviews …, 2020 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) pandemic is concerning for patients with
neuroimmunological diseases who are receiving immunotherapy. Uncertainty remains …

Incidence, associated factors and clinical impact of severe infections in a large, multicentric cohort of patients with systemic lupus erythematosus

Í Rúa-Figueroa, J López-Longo… - Seminars in arthritis and …, 2017 - Elsevier
Objectives To estimate the incidence of severe infection and investigate the associated
factors and clinical impact in a large systemic lupus erythematosus (SLE) retrospective …

Complement, infection, and autoimmunity

P Conigliaro, P Triggianese, E Ballanti… - Current Opinion in …, 2019 - journals.lww.com
The relationship between the complement system and autoimmunity appears paradoxical as
both the deficiency and the activation contribute to inducing autoimmune diseases. In these …

KDIGO 2024 Clinical Practice Guideline for the management of LUPUS NEPHRITIS

BH Rovin, IM Ayoub, TM Chan, ZH Liu… - Kidney …, 2024 - kidney-international.org
This article is published as part of a supplement sponsored by Kidney Disease: Improving
Global Outcomes (KDIGO). The opinions or views expressed in this supplement are those of …