Loss of ninein interferes with osteoclast formation and causes premature ossification

T Gilbert, C Gorlt, M Barbier, B Duployer, M Plozza… - Elife, 2024 - elifesciences.org
Ninein is a centrosome protein that has been implicated in microtubule anchorage and
centrosome cohesion. Mutations in the human NINEIN gene have been linked to Seckel …

A novel perspective of calvarial development: the cranial morphogenesis and differentiation regulated by dura mater

D Li, X Jiang, J Xiao, C Liu - Frontiers in Cell and Developmental …, 2024 - frontiersin.org
There are lasting concerns on calvarial development because cranium not only
accommodates the growing brain, but also safeguards it from exogenous strikes. In the past …

Insights into Craniofacial Development and Anomalies: Exploring Fgf Signaling in Zebrafish Models

R Pereur, E Dambroise - Current Osteoporosis Reports, 2024 - Springer
Abstract Purpose of Review To illustrate the value of using zebrafish to understand the role
of the Fgf signaling pathway during craniofacial skeletal development under normal and …

Regulation of bone homeostasis: signaling pathways and therapeutic targets

Z Wu, W Li, K Jiang, Z Lin, C Qian, M Wu, Y Xia… - MedComm, 2024 - Wiley Online Library
As a highly dynamic tissue, bone is continuously rebuilt throughout life. Both bone formation
by osteoblasts and bone resorption by osteoclasts constitute bone reconstruction …

Overexpression of Fgf18 in cranial neural crest cells recapitulates Pierre Robin sequence in mice

Y Lv, Q Wang, C Lin, X Zheng, Y Zhang… - Frontiers in Cell and …, 2024 - frontiersin.org
The pivotal role of FGF18 in the regulation of craniofacial and skeletal development has
been well established. Previous studies have demonstrated that mice with deficiency in …