Inflammation is a complex biologic response that is essential for eliminating microbial
pathogens and repairing tissue after injury. AKI associates with intrarenal and systemic …

Acute kidney injury (AKI) prolongs hospital stay and increases mortality in various clinical
settings. Ischaemia–reperfusion injury (IRI), nephrotoxic agents and infection leading to …

Ischemia reperfusion injury (IRI) is a common cause of acute kidney injury (AKI). The role of
N6-methyladenosine (m6A) modification in AKI remains unclear. Here, we characterize the …

The acutely injured mammalian kidney mounts a cellular and molecular response to repair
itself. However, in patchy regions such intrinsic processes are impaired and dysregulated …

Increasing evidence has demonstrated the bidirectional link between acute kidney injury
(AKI) and chronic kidney disease (CKD) such that, in the clinical setting, the new concept of …

Renal dendritic cells (DCs) and macrophages represent a constitutive, extensive and
contiguous network of innate immune cells that provide sentinel and immune-intelligence …

Acute kidney injury (AKI) remains a major clinical event with rising incidence, severity, and
cost; it now has a morbidity and mortality exceeding acute myocardial infarction. There is …

Acute kidney injury (AKI) and chronic kidney diseases are associated with high mortality and
morbidity. Although the underlying mechanisms determining the transition from acute to …

Intestinal microbiota impacts the host immune system and influences the outcomes of
chronic diseases. However, it remains uncertain whether acute kidney injury (AKI) impacts …

The development of the T-and natural killer (NK) cell growth factor IL-2 has been a sentinel
force ushering in the era of immunotherapy in cancer. With the advent of clinical grade …