Background Anatomic and physiological similarities to the human make swine an excellent
large animal model for human health and disease. Methods Cloning from a modified …

During the last two decades, pigs have been used to develop some of the most important
large animal models for biomedical research. Advances in pig genome research, genetic …

In the past few years, new technologies have arisen that enable higher efficiency of gene
editing. With the increase ease of using gene editing technologies, it is important to consider …

In the quest to address the critical shortage of donor organs for transplantation,
xenotransplantation stands out as a promising solution, offering a more abundant supply of …

The objective was to use dual markers to accurately select genetically modified donor cells
and ensure that the resulting somatic cell nuclear transfer kids born were transgenic. Fetal …

Porcine somatic cell nuclear transfer (SCNT) has been used extensively to create
genetically modified pigs, but the efficiency of the methodology is still low. It has been …

the present disclosure in some aspects thereof, relates to isolated naive pluripotent stem
cell, novel culture medium which can be used to generate same and methods of generating …

Germ cells are alternative sources for deriving pluripotent stem cells. Because embryonic
germ cells (EGCs) possess physiological and developmental features similar to those of …

Xenotransplantation literature update June October 2010 Page 1 Literature Update
Xenotransplantation literature update June – October 2010 Reviews During the period June …

摘要本试验旨在建立一个适合于巴马小型猪转基因克隆胚胎生产的高效融合/激活体系,
为生产足量的转基因克隆胚胎奠定基础. 把hGFAP-DsRed 基因转入巴马小型猪肾脏成纤维细胞 …