Recent studies show that pre-follicular mouse oogenesis takes place in germline cysts,
highly conserved groups of oogonial cells connected by intercellular bridges that develop as …

Highlights•The GRC's absence from the soma might mitigate germline-soma conflict.•Sex-
specific copy number differences highlight the GRC's distorted transmission.•A …

Reproductive success hinges on precisely coordinated meiosis, yet our understanding of
how structural rearrangements of chromatin and phase transitions during meiosis are …

Darwin recognized that 'a grand and almost untrodden field of inquiry will be opened, on the
causes and laws of variation.'However, because the Modern Synthesis assumes that the …

Meiosis is associated with genetic changes in the genome—via recombination, gene
conversion, and mutations. The occurrence of gene conversion and mutations during …

Meiotic recombination is one of the main sources of genetic variation, a fundamental factor
in the evolutionary adaptation of sexual eukaryotes. Yet, the role of variation in …

The intergenerational transmission of educational attainment from parents to their children is
one of the most important and studied relationships in social science. Longitudinal studies …

In eutherian mammals, hundreds of programmed DNA double-strand breaks (DSBs) are
generated at the onset of meiosis. The DNA damage response is then triggered. Although …

Histone post-translational modifications, such as phosphorylation, methylation, acetylation,
and ubiquitination, play vital roles in various chromatin-based cellular processes. Meiosis is …

Gamete production in most animal species is initiated within an evolutionarily ancient
multicellular germline structure, the germline cyst, whose interconnected premeiotic cells …