Traumatic brain injury (TBI) is the leading cause for high morbidity and mortality rates in
young adults, survivors may suffer from long-term physical, cognitive, and/or psychological …

Abstract The Blood-Brain Barrier (BBB) significantly impedes drug delivery to the central
nervous system. Nanotechnology, especially surface-functionalized lipid nanoparticles …

Currently, nanoparticles (NPs) are extensively applied in the diagnosis and treatment of
neurodegenerative diseases (NDs). With the rapid development and increasing exposure to …

In this study, a novel dual-drug carrier for the co-administration of an anti-inflammatory and
antibiotic agent consisting of core-shell nanofibers for the treatment of cornea alkali burns …

Breast cancer (BC) remains a significant health burden worldwide, necessitating the
development of innovative therapeutic strategies. The B-cell lymphoma 2 (Bcl-2) family …

Simple Summary Glioblastoma's poor prognosis calls for the discovery of newer, more
efficacious management and treatment methods. This review collates and examines how the …

Metformin is a multipotential compound for treating diabetes II and controlling hormonal
acne and skin cancer. This study was designed to enhance metformin skin penetration in …

Complexity associated with the aberrant physiology of traumatic brain injury (TBI) makes its
therapeutic targeting vulnerable. The underlying mechanisms of pathophysiology of TBI are …

Objective The purpose of this study was to prepare and evaluate chitosan (CS) gel
containing metformin hydrochloride (MET)-loaded polycaprolactone (PCL) nanoparticles …

Introduction. Recognizing the importance of medicinal plants and the absence of specific
medications for traumatic brain injury (TBI) treatment, this study was conducted to evaluate …