The evolution of spliceosomal introns: patterns, puzzles and progress

S William Roy, W Gilbert - Nature Reviews Genetics, 2006 - nature.com
The origins and importance of spliceosomal introns comprise one of the longest-abiding
mysteries of molecular evolution. Considerable debate remains over several aspects of the …

Processed pseudogenes: characteristics and evolution.

EF Vanin - Annual review of genetics, 1985 - europepmc.org
The processed pseudogenes reported to date fall into three categories: those that are a
complete copy of the mRNA transcribed from the functional gene, those that are only a …

Evaluation of two main RNA-seq approaches for gene quantification in clinical RNA sequencing: polyA+ selection versus rRNA depletion

S Zhao, Y Zhang, R Gamini, B Zhang, D Von Schack - Scientific reports, 2018 - nature.com
To allow efficient transcript/gene detection, highly abundant ribosomal RNAs (rRNA) are
generally removed from total RNA either by positive polyA+ selection or by rRNA depletion …

Influence of RNA extraction methods and library selection schemes on RNA-seq data

M Sultan, V Amstislavskiy, T Risch, M Schuette… - BMC genomics, 2014 - Springer
Background Gene expression analysis by RNA sequencing is now widely used in a number
of applications surveying the whole transcriptomes of cells and tissues. The recent …

Origin of the human L1 elements: proposed progenitor genes deduced from a consensus DNA sequence

AF Scott, BJ Schmeckpeper, M Abdelrazik, CT Comey… - Genomics, 1987 - Elsevier
A consensus sequence for the human long interspersed repeated DNA element, L1H8
(LINE or KpnI sequence), is presented. The sequence contains two open reading frames …

Reverse gyrase—a topoisomerase which introduces positive superhelical turns into DNA

A Kikuchi, K Asai - Nature, 1984 - nature.com
An enzymatic activity which converts closed circular DNA into a positively supercoiled form
is present in cellular extracts of Sulfolobus, an acidothermophilic archaebacterium. This …

Mechanisms of nonhomologous recombination in mammalian cells

DB Roth, TN Porter, JH Wilson - Molecular and cellular biology, 1985 - Am Soc Microbiol
The primary mechanism of nonhomologous recombination in transfected DNA involves
breakage followed by end joining. To probe the joining step in more detail, linear simian …

Small nuclear RNAs: RNA sequences, structure, and modifications

R Reddy, H Busch - Structure and function of major and minor small …, 1988 - Springer
All eukaryotic cells contain multiple small nuclear RNAs, designated U-sn At present ten U-
snRNAs have been identified; they account for about 1% total mammalian cellular RNA. Of …

Comparison of three actin-coding sequences in the mouse; evolutionary relationships between the actin genes of warm-blooded vertebrates

S Alonso, A Minty, Y Bourlet, M Buckingham - Journal of Molecular …, 1986 - Springer
We have determined the sequences of three recombinant cDNAs complementary to different
mouse actin mRNAs that contain more than 90% of the coding sequences and complete or …

The origin and evolution of retroposons

JH Rogers - International review of cytology, 1985 - Elsevier
Publisher Summary This chapter describes the origin and evolution of retroposons. It deals
with two of them which operate on very different timescales:(1) RNA splicing (particularly …