Vaccine candidates for leishmaniasis: a review

R Nagill, S Kaur - International immunopharmacology, 2011 - Elsevier
Leishmaniasis is a diverse group of clinical syndromes caused by protozoan parasites of the
genus Leishmania. The clinical manifestation of the disease varies from self-limiting …

[HTML][HTML] Vaccination in leishmaniasis: a review article

L Abdellahi, F Iraji, A Mahmoudabadi… - Iranian Biomedical …, 2022 - ncbi.nlm.nih.gov
Leishmaniasis is caused by protozoan Leishmania parasites that are transmitted through
female sandfly bites. The disease is predominantly endemic to the tropics and semi-tropics …

Immunological perspectives of leishmaniasis

S Nylén, S Gautam - Journal of global infectious diseases, 2010 - journals.lww.com
Leishmania parasites have been widely used in experimental models to understand
generation, maintenance and failure of immune responses underlying resistance and …

New World cutaneous leishmaniasis: updated review of current and future diagnosis and treatment

P Mitropoulos, P Konidas, M Durkin-Konidas - Journal of the American …, 2010 - Elsevier
BACKGROUND: Cutaneous leishmaniasis (CL) has traditionally been underrecognized and
underreported. Improved awareness is warranted as the number of cases has increased as …

Leishmaniasis: current treatment and prospects for new drugs and vaccines

L Kedzierski, A Sakthianandeswaren… - Current medicinal …, 2009 - ingentaconnect.com
Leishmaniasis is a disease that ranges in severity from skin lesions to serious disfigurement
and fatal systemic infection. WHO estimates that the disease results in 2 million new cases a …

Intracellular replication-deficient Leishmania donovani induces long lasting protective immunity against visceral leishmaniasis

A Selvapandiyan, R Dey, S Nylen… - The Journal of …, 2009 - journals.aai.org
No vaccine is currently available for visceral leishmaniasis (VL) caused by Leishmania
donovani. This study addresses whether a live attenuated centrin gene-deleted L. donovani …

Vaccination using live attenuated Leishmania donovani centrin deleted parasites induces protection in dogs against Leishmania infantum

JA Fiuza, S Gannavaram, H da Costa Santiago… - Vaccine, 2015 - Elsevier
Live attenuated Leishmania donovani parasites such as LdCen−/− have been shown elicit
protective immunity against leishmanial infection in mice and hamster models. Previously …

Development of vaccines against visceral leishmaniasis

KJ Evans, L Kedzierski - Journal of tropical medicine, 2012 - Wiley Online Library
Leishmaniasis is a neglected disease resulting in a global morbidity of 2,090 thousand
Disability‐Adjusted Life Years and a mortality rate of approximately 60,000 per year. Among …

Leishmania vaccine development: exploiting the host–vector–parasite interface

SG Reed, RN Coler, D Mondal, S Kamhawi… - Expert review of …, 2016 - Taylor & Francis
Visceral leishmaniasis (VL) is a disease transmitted by phlebotomine sand flies, fatal if
untreated, and with no available human vaccine. In rodents, cellular immunity to Leishmania …

Immunity to visceral leishmaniasis using genetically defined live‐attenuated parasites

A Selvapandiyan, R Dey, S Gannavaram… - Journal of tropical …, 2012 - Wiley Online Library
Leishmaniasis is a protozoan parasitic disease endemic to the tropical and subtropical
regions of the world, with three major clinical forms, self‐healing cutaneous leishmaniasis …