Rotaviruses cause life-threatening gastroenteritis in children worldwide; the enormous
disease burden has focused efforts to develop vaccines and led to the discovery of novel …

Enteric viruses display intricate adaptations to the host mucosal immune system to
successfully reproduce in the gastrointestinal tract and cause maladies ranging from …

Metagenomic studies show that diverse resident viruses inhabit the healthy gut; however,
little is known about the role of these viruses in the maintenance of gut homeostasis. We …

Abstract Regulatory CD4+ Foxp3+ T cells (Tregs) are key regulators of inflammatory
responses and control the magnitude of cellular immune responses to viral infections …

CD8 T‐lymphocytes are effector cells of cholangiocyte injury in human and in rhesus
rotavirus (RRV)‐induced experimental biliary atresia (BA). Here we hypothesize that …

Bacterial ghosts may be generated by the controlled expression of the phiX174 lysis gene E
in Gram-negative bacteria and they are intriguing vaccine candidates since ghosts retain …

Regulatory T cells (Tregs) are indispensable for immune homeostasis and the prevention of
autoimmunity. In the context of infectious diseases, Tregs are multidimensional. Here, we …

The aim of the present study was to investigate the changes in the cytokine expression of
peripheral regulatory T cells (Treg) and T helper 17 (Th17) cells in children with rotavirus …

Abstract CD4+ CD25+ FoxP3+ regulatory T cells (Tregs) are critical for immune homeostasis
and tolerance. However, because of their capacity to suppress antigen presenting cells …

Paracoccidioidomycosis is a granulomatous systemic mycosis endemic in Brazil and other
Latin America countries. A DNA vaccine encoding the immunoprotective peptide 10 (P10) …