Diffuse optics for tissue monitoring and tomography

T Durduran, R Choe, WB Baker… - Reports on progress in …, 2010 - iopscience.iop.org
This review describes the diffusion model for light transport in tissues and the medical
applications of diffuse light. Diffuse optics is particularly useful for measurement of tissue …

Diffuse optical imaging of the healthy and diseased breast: a systematic review

DR Leff, OJ Warren, LC Enfield, A Gibson… - Breast cancer research …, 2008 - Springer
Screening X-ray mammography is limited by false positives and negatives leading to
unnecessary physical and psychological morbidity. Diffuse Optical Imaging using harmless …

Modified Beer-Lambert law for blood flow

WB Baker, AB Parthasarathy, DR Busch… - Biomedical optics …, 2014 - opg.optica.org
We develop and validate a Modified Beer-Lambert law for blood flow based on diffuse
correlation spectroscopy (DCS) measurements. The new formulation enables blood flow …

Predicting response to breast cancer neoadjuvant chemotherapy using diffuse optical spectroscopy

A Cerussi, D Hsiang, N Shah… - Proceedings of the …, 2007 - National Acad Sciences
Diffuse optical spectroscopy (DOS) and imaging are emerging diagnostic techniques that
quantitatively measure the concentration of deoxy-hemoglobin (ctHHb), oxy-hemoglobin …

Noninvasive optical measures of CBV, StO2, CBF index, and rCMRO2 in human premature neonates' brains in the first six weeks of life

N Roche‐Labarbe, SA Carp, A Surova… - Human brain …, 2010 - Wiley Online Library
With the causes of perinatal brain injuries still unclear and the probable role of
hemodynamic instability in their etiology, bedside monitoring of neonatal cerebral …

Direct measurement of tissue blood flow and metabolism with diffuse optics

RC Mesquita, T Durduran, G Yu… - … of the Royal …, 2011 - royalsocietypublishing.org
Diffuse optics has proven useful for quantitative assessment of tissue oxy-and
deoxyhaemoglobin concentrations and, more recently, for measurement of microvascular …

Differentiation of benign and malignant breast tumors by in-vivo three-dimensional parallel-plate diffuse optical tomography

R Choe, SD Konecky, A Corlu, K Lee… - … of biomedical optics, 2009 - spiedigitallibrary.org
We have developed a novel parallel-plate diffuse optical tomography (DOT) system for three-
dimensional in vivo imaging of human breast tumor based on large optical data sets. Images …

Validation of diffuse correlation spectroscopy for muscle blood flow with concurrent arterial spin labeled perfusion MRI

G Yu, TF Floyd, T Durduran, C Zhou, J Wang… - Optics express, 2007 - opg.optica.org
Calf blood flow was measured simultaneously in healthy human subjects (n= 7) during cuff
inflation and deflation using near-infrared diffuse correlation spectroscopy (DCS) and …

Diffuse optical correlation tomography of cerebral blood flow during cortical spreading depression in rat brain

C Zhou, G Yu, D Furuya, JH Greenberg, AG Yodh… - Optics express, 2006 - opg.optica.org
Diffuse optical correlation methods were adapted for three-dimensional (3D) tomography of
cerebral blood flow (CBF) in small animal models. The image reconstruction was optimized …

Cerebral hemodynamics in preterm infants during positional intervention measured with diffuse correlation spectroscopy and transcranial Doppler ultrasound

EM Buckley, NM Cook, T Durduran, MN Kim, C Zhou… - Optics …, 2009 - opg.optica.org
Four very low birth weight, very premature infants were monitored during a 12? postural
elevation using diffuse correlation spectroscopy (DCS) to measure microvascular cerebral …