Severe hemorrhage has posed a serious threat to the health and even life of civilian and
military populations and brought serious economic losses. Consequently, it is imperative to …

Uncontrolled traumatic bleeding can lead to death due to excessive blood loss within
minutes. Early intervention is crucial to save lives, making timely and effective hemostasis is …

The COVID-19 pandemic has major implications for blood transfusion. There are uncertain
patterns of demand, and transfusion institutions need to plan for reductions in donations and …

Early administration of blood products following severe trauma is pivotal for establishing
hemostasis and achieving successful outcomes. Platelet transfusions, in particular, provide …

ABSTRACT BACKGROUND Cold (4° C)‐stored platelets are currently under investigation
for transfusion in bleeding patients. It is currently unknown how long cold‐stored platelets …

Background Platelet (PLT) product transfusion is a life-saving therapy for actively bleeding
patients. There is an urgent need to maintain PLT function and extend shelf life to improve …

Blood is donated either as whole blood, with subsequent component processing, or through
the use of apheresis devices that extract one or more components and return the rest of the …

Background Refrigeration, or cold‐storage, of platelets may be beneficial to extend the
limited shelf‐life of conventionally stored platelets and support transfusion protocols in rural …

Blood is a fluid connective tissue where living cells are suspended in noncellular liquid
matrix. The cellular components of blood render gas exchange (RBCs), immune …

Platelets are currently stored at room temperature before transfusion to maximize circulation
time. This approach has numerous downsides, including limited storage duration, bacterial …