The role of cellular senescence in ovarian aging

JD Hense, JVV Isola, DN Garcia, LS Magalhães… - npj Aging, 2024 - nature.com
This review explores the relationship between ovarian aging and senescent cell
accumulation, as well as the efficacy of senolytics to improve reproductive longevity …

Circadian rhythms and breast cancer: unraveling the biological clock's role in tumor microenvironment and ageing

Y Yan, L Su, S Huang, Q He, J Lu, H Luo, K Xu… - Frontiers in …, 2024 - frontiersin.org
Breast cancer (BC) is one of the most common and fatal malignancies among women
worldwide. Circadian rhythms have emerged in recent studies as being involved in the …

Rheumatoid arthritis and risk of site-specific cancers: Mendelian randomization study in European and East Asian populations

S Yuan, J Chen, X Ruan, M Vithayathil, S Kar… - Arthritis Research & …, 2022 - Springer
Background The associations of rheumatoid arthritis (RA) with risk of site-specific cancers
beyond lymphohematopoietic cancer have been scarcely explored. We conducted a …

The role of Selenium and Manganese in the formation, diagnosis and treatment of cervical, endometrial and ovarian Cancer

A Golara, M Kozłowski, P Guzik, S Kwiatkowski… - International Journal of …, 2023 - mdpi.com
Selenium (Se) and manganese (Mn) are essential micronutrients that are important
elements of cell metabolism. They are involved in the composition of enzyme systems and …

Menopause is associated with postprandial metabolism, metabolic health and lifestyle: The ZOE PREDICT study

KM Bermingham, I Linenberg, WL Hall, K Kadé… - …, 2022 - thelancet.com
Background The menopause transition is associated with unfavourable alterations in health.
However, postprandial metabolic changes and their mediating factors are poorly …

Identification of the most common BRCA alterations through analysis of germline mutation databases: is droplet digital PCR an additional strategy for the assessment …

A Lavoro, A Scalisi, S Candido… - International …, 2022 - spandidos-publications.com
Breast and ovarian cancer represent two of the most common tumor types in females
worldwide. Over the years, several non‑modifiable and modifiable risk factors have been …

Time trend of global uterine cancer burden: an age-period-cohort analysis from 1990 to 2019 and predictions in a 25-year period

L Yang, Y Yuan, R Zhu, X Zhang - BMC women's health, 2023 - Springer
Background Uterine cancer remains a serious medical problem worldwide. This study aimed
to explore the global time trends of uterine cancer burden using the age-period-cohort …

Elucidating the roles of the mammary and gut microbiomes in breast cancer development

C Hoskinson, RY Jiang, LT Stiemsma - Frontiers in Oncology, 2023 - frontiersin.org
The mammary microbiome is a newly characterized bacterial niche that might offer
biological insight into the development of breast cancer. Together with in-depth analysis of …

[HTML][HTML] Neurokinin 1/3 receptor antagonists for menopausal women: A current systematic review and insights into the investigational non-hormonal therapy

F Hassan, A Saleem, SS Samuel, Z Sarfraz, A Sarfraz… - Medicine, 2023 - journals.lww.com
Background: Over 75% of menopausal women experience vasomotor symptoms (VMS),
such as night sweats and hot flashes. Despite the prevalence of these symptoms, there is …

[HTML][HTML] Evaluation of the Potential Beneficial Effects of Ferula communis L. Extract Supplementation in Postmenopausal Discomfort

R Macrì, J Maiuolo, F Scarano, V Musolino, A Fregola… - Nutrients, 2024 - mdpi.com
Peri-menopausal discomfort can have a detrimental effect on the physical health of women
due to physiological and behavioral changes. Estrogen and progesterone-based hormone …