Multiscale modeling shows how 2'-deoxy-ATP rescues ventricular function in heart failure
2'-deoxy-ATP (dATP) improves cardiac function by increasing the rate of crossbridge cycling
and Ca 2+ transient decay. However, the mechanisms of these effects and how therapeutic …
and Ca 2+ transient decay. However, the mechanisms of these effects and how therapeutic …
[PDF][PDF] Investigating the Multiscale Impact of Deoxyadenosine Triphosphate (dATP) on Pulmonary Arterial Hypertension (PAH) Induced Heart Failure
Pulmonary arterial hypertension (PAH) is a rare, yet aggressive disease with a 3-year
survival rate of 54.9% for humans [6]. This life-threatening disease is characterized by …
survival rate of 54.9% for humans [6]. This life-threatening disease is characterized by …