Repeated, episodic bouts of skeletal muscle contraction undertaken frequently as structured
exercise training are a potent stimulus for physiological adaptation in many organs …

Mechanisms underlying mechanical overload-induced skeletal muscle hypertrophy have
been extensively researched since the landmark report by Morpurgo (1897) of “work …

Exercise has long been known for its active role in improving physical fitness and sustaining
health. Regular moderate-intensity exercise improves all aspects of human health and is …

Androgens are an important and diverse group of steroid hormone molecular species. They
play varied functional roles, such as the control of metabolic energy fate and partition, the …

JAK/STAT signaling pathway is one of the important regulatory signaling cascades for the
myriad of cellular processes initiated by various types of ligands such as growth factors …

Maintenance of skeletal muscle mass throughout the life course is key for the regulation of
health, with physical activity a critical component of this, in part, due to its influence upon key …

The maintenance of muscle homeostasis is vital for life and health. Skeletal muscle atrophy
not only seriously reduces people's quality of life and increases morbidity and mortality, but …

Resistance training is frequently performed with the goal of stimulating muscle hypertrophy.
Due to the key roles motor unit recruitment and mechanical tension play to induce muscle …

Biological sex is a primary determinant of athletic performance because of fundamental sex
differences in anatomy and physiology dictated by sex chromosomes and sex hormones …

Astrocytomas and, in particular, their most severe form, glioblastoma, are the most
aggressive primary brain tumors and those with the poorest vital prognosis. Standard …