Plant cytochrome P450s: Role in stress tolerance and potential applications for human welfare

A Singh, R Panwar, P Mittal, MI Hassan… - International Journal of …, 2021 - Elsevier
Cytochrome P450s (CYPs) are a versatile group of enzymes and one of the largest families
of proteins, controlling various physiological processes via biosynthetic and detoxification …

Engineering medicinal plant-derived CYPs: a promising strategy for production of high-valued secondary metabolites

A Sethi, A Bhandawat, PK Pati - Planta, 2022 - Springer
Main conclusion Cytochorme P450s (CYPs) play a critical role in the catalysis of secondary
metabolite biosynthetic pathways. For their commercial use, various strategies for metabolic …

Association genetics of phenolic needle compounds in Norway spruce with variable susceptibility to needle bladder rust

A Ganthaler, W Stöggl, S Mayr, I Kranner… - Plant Molecular …, 2017 - Springer
Key message Accumulation of phenolic needle metabolites in Norway spruce is regulated
by many genes with small and additive effects and is correlated with the susceptibility …

Transcriptome analysis identifies strong candidate genes for ginsenoside biosynthesis and reveals its underlying molecular mechanism in Panax ginseng CA Meyer

M Zhao, Y Lin, Y Wang, X Li, Y Han, K Wang, C Sun… - Scientific Reports, 2019 - nature.com
Abstract Ginseng, Panax ginseng CA Meyer, is one of the most important medicinal herbs for
human health and medicine in which ginsenosides are known to play critical roles. The …

Identification of anther thermotolerance genes by the integration of linkage and association analysis in maize

Y Feng, X Li, Y Qin, Y Li, Z Yang, X Xiong… - The Plant …, 2024 - Wiley Online Library
Maize is one of the world's most important staple crops, yet its production is increasingly
threatened by the rising frequency of high‐temperature stress (HTS). To investigate the …

Compartmentalized sesquiterpenoid biosynthesis and functionalization in the Chlamydomonas reinhardtii plastid

S Gutiérrez, S Overmans, GB Wellman… - …, 2024 - Wiley Online Library
Terpenoids play key roles in cellular metabolism and can have specialized functions. Their
heterologous production in microbial hosts offers an alternative to natural extraction. Here …

De novo leaf and root transcriptome analysis to explore biosynthetic pathway of Celangulin V in Celastrus angulatus maxim

W Li, R Xu, X Yan, D Liang, L Zhang, X Qin, Q Caiyin… - BMC genomics, 2019 - Springer
Abstract Background Celastrus angulatus Maxim is a kind of crucial and traditional
insecticidal plant widely distributed in the mountains of southwest China. Celangulin V is the …

Prediction of the reaction mechanisms of sesquiterpene coumarin synthases supports a direct evolutionary link with triterpene biosynthesis

MJ Stephenson, PE Brodelius - Phytochemistry Reviews, 2025 - Springer
Sesquiterpene coumarins are primarily produced by plants of the Apiaceae and Asteraceae
families. Farnesylation of 7-hydroxycoumarins such as umbelliferone, scopoletin or …

Kaurenoic acid: a diterpene with a wide range of biological activities

N Villa-Ruano, E Lozoya-Gloria… - Studies in natural …, 2016 - Elsevier
Beyond its vital role in plant metabolism, kaurenoic acid (KA) has acquired remarkable
importance in the fields of medicinal chemistry and pharmacology. Here, we show and …

Characterization and overexpression of sterol Δ22-desaturase, a key enzyme modulates the biosyntheses of stigmasterol and withanolides in Withania somnifera (L.) …

A Sharma, S Rana, GA Rather, P Misra, MK Dhar… - Plant Science, 2020 - Elsevier
Withanolides constitute an extensive and vital class of metabolites displaying wide array of
structural and therapeutic properties with unique side-chain modifications. These show …