Target based chemotherapeutic advancement of ruthenium complexes

BK Kundu, S Mukhopadhyay - Coordination Chemistry Reviews, 2021 - Elsevier
Over the last few years, great emphasis has been given to develop ruthenium complexes to
act as target specified chemotherapeutic agents. Indeed, there are few reviews available …

H2S Donors and Their Use in Medicinal Chemistry

E Magli, E Perissutti, V Santagada, G Caliendo… - Biomolecules, 2021 - mdpi.com
Hydrogen sulfide (H2S) is a ubiquitous gaseous signaling molecule that has an important
role in many physiological and pathological processes in mammalian tissues, with the same …

[HTML][HTML] Polysulfide-mediated sulfhydration of SIRT1 prevents diabetic nephropathy by suppressing phosphorylation and acetylation of p65 NF-κB and STAT3

HJ Sun, SP Xiong, X Cao, L Cao, MY Zhu, ZY Wu… - Redox biology, 2021 - Elsevier
Diabetic kidney disease is known as a major cause of chronic kidney disease and end stage
renal disease. Polysulfides, a class of chemical agents with a chain of sulfur atoms, are …

Hydrogen sulfide: recent progression and perspectives for the treatment of diabetic nephropathy

HJ Sun, ZY Wu, L Cao, MY Zhu, TT Liu, L Guo, Y Lin… - Molecules, 2019 - mdpi.com
Diabetic kidney disease develops in approximately 40% of diabetic patients and is a major
cause of chronic kidney diseases (CKD) and end stage kidney disease (ESKD) worldwide …

Gas and gas-generating nanoplatforms in cancer therapy

YZ Jing, SJ Li, ZJ Sun - Journal of Materials Chemistry B, 2021 - pubs.rsc.org
Gas therapy is the usage of certain gases with special therapeutic effects for the treatment of
diseases. Hydrogen (H2), nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide …

Fighting oxidative stress with sulfur: Hydrogen sulfide in the renal and cardiovascular systems

JJ Scammahorn, ITN Nguyen, EM Bos, H Van Goor… - Antioxidants, 2021 - mdpi.com
Hydrogen sulfide (H2S) is an essential gaseous signaling molecule. Research on its role in
physiological and pathophysiological processes has greatly expanded. Endogenous …

H2S-based fluorescent imaging for pathophysiological processes

TT Jia, Y Zhang, JT Hou, H Niu, S Wang - Frontiers in Chemistry, 2023 - frontiersin.org
Hydrogen sulfide (H2S), as an important endogenous signaling molecule, plays a vital role
in many physiological processes. The abnormal behaviors of hydrogen sulfide in organisms …

Role of hydrogen sulfide and polysulfides in neurological diseases: focus on protein S-persulfidation

HJ Sun, ZY Wu, XW Nie, JS Bian - Current …, 2021 - ingentaconnect.com
Hydrogen sulfide (H2S) and hydrogen polysulfides are recognized as important signaling
molecules that are generated physiologically in the body, including the central nervous …

A Trisulfide Bond Containing Biodegradable Polymer Delivering Pt(IV) Prodrugs to Deplete Glutathione and Donate H2S to Boost Chemotherapy and Antitumor …

X Li, J Cai, H Zhang, S Sun, S Zhao, Z Wang, X Nie… - ACS …, 2024 - ACS Publications
The clinical application of cisplatin (CisPt) is limited by its dose-dependent toxicity. To
overcome this, we developed reduction-responsive nanoparticles (NP (3S) s) for the …

Therapeutic potential of sulfur-containing natural products in inflammatory diseases

X Cao, L Cao, W Zhang, R Lu, JS Bian, X Nie - Pharmacology & …, 2020 - Elsevier
Owing to the prevalence of chronic inflammation and its related disorders, there is a demand
for novel therapeutic agents capable of preventing or suppressing inflammation. Natural …