Design, synthesis and QSAR study of novel isatin analogues inspired Michael acceptor as potential anticancer compounds

J Wang, D Yun, J Yao, W Fu, F Huang, L Chen… - European journal of …, 2018 - Elsevier
Molecular hybridization is considered as an effective tactic to develop drugs for the treatment
of cancer. A series of novel hybrid compounds of isatin and Michael acceptor were designed …

Highly Regioselective Synthesis of Oxindolyl-Pyrroles and Quinolines via a One-Pot, Sequential Meyer–Schuster Rearrangement, Anti-Michael Addition/C(sp3)–H …

S Yaragorla, R Dada, P Rajesh, M Sharma - ACS omega, 2018 - ACS Publications
A one-pot, sequential Meyer–Schuster (MS) rearrangement of oxindole-derived propargyl
alcohols to the corresponding α, β-unsaturated enones and their anti-Michael addition …

Synthesis, characterization, and in vitro biological studies of some novel pyran fused pyrimidone derivatives

PT Mistry, NR Kamdar, DD Haveliwala… - Journal of Heterocyclic …, 2012 - Wiley Online Library
Abstract A variety of pyrano [2, 3‐d] pyrimidine‐5‐one derivatives 5, 5a, 5b, 5c, 5d, 5e, 5f, 5g,
5h, 5i, 5j, 6, 6a, 6b, 6c, 6d, 6e, 6f, 6g, 6h, 6i, 6j have been synthesized from 6‐amino‐4 …

Inorganic–organic hybrid silica based tin (II) catalyst: Synthesis, characterization and application in one-pot three-component Mannich reaction

RK Sharma, D Rawat, G Gaba - Catalysis Communications, 2012 - Elsevier
Inorganic–organic hybrid material catalyzed one-pot three-component Mannich reaction of
ketones with aromatic aldehydes and different amines at ambient temperatures afforded β …

Efficient Protocol for Novel Hybrid Pyrimidines Synthesis: Antiproliferative Activity, DFT Analyses, and Molecular Docking Studies

IO Althobaiti, MSM Alserhani, WAA Arafa… - ACS …, 2023 - ACS Publications
An efficient, microwave/ultrasound-irradiated synthesis of novel chromenopyrimidines has
been established. 2-Amino-5-oxo-4-(thiophen-2-yl)-5, 6, 7, 8-tetrahydro-4 H-chromene-3 …

Regioselective synthesis of biologically important scaffold spiro [indole-perimidines]: an antitumor agents

K Arya, A Dandia - Letters in Organic chemistry, 2007 - benthamdirect.com
Regioselective synthesis of spiro [indole-3 (3H), 2'(3H) perimidine] 2'(1H) one (4a-e) for
potential application in cancer treatment\under conventionally and microwave irradiation …

Mesoporous silica nanoparticles (MSNs) as an efficient and reusable nanocatalyst for synthesis of β-amino ketones through one-pot three-component Mannich …

Z Nasresfahani, MZ Kassaee, M Nejati-Shendi, E Eidi… - RSC …, 2016 - pubs.rsc.org
Mesoporous silica nanoparticles (MSNs) proved efficient and reusable in the catalytic
synthesis of β-amino ketones, through three-component Mannich reaction of ketones …

[PDF][PDF] Pollutants Generated from Pharmaceutical Processes and Microwave Assisted Synthesis as Possible Solution for Their Reduction- A Mini Review

G Yaqub, A Hamid, S Iqbal - Nature, Environment and Pollution …, 2012 - neptjournal.com
In this review article we have briefly summarized the pharmaceutical processes and the
pollutants ie, VOCs and other air emissions from reactors and distillation assemblies …

Green method for synthesis of 3-[2-(substituted-phenyl)-2-oxo ethylidene]-1, 3-dihydro-indol-2-one and their in vitro antimicrobial activity

AP Acharya, RD Kamble, SD Patil, SV Hese… - Research on Chemical …, 2015 - Springer
The cross-aldol condensation between isatin (I) and substituted acetophenone (IIa–e) in one-
pot reaction afforded 3-[2-(substituted-phenyl)-2-oxo-ethylidene]-1, 3-dihydro-indol-2-one …

Microwave-Assisted Synthesis of Spiro(cycloalkane thiazolo-s-tetrazine)

RK Behera, A Pati, M Patra… - Phosphorus, Sulfur, and …, 2009 - Taylor & Francis
Microwave irradiation of cyclic ketones with thiocarbohydrazide furnish the corresponding s-
tetrazine derivatives 1a–d, which upon irradiation with chloroacetic acid and sodium acetate …