Simple Summary Non-melanoma skin cancer (NMSC) is the main type of cancer in the
Caucasian population, and the number of cases continues to rise. Research mostly focuses …

Basal cell carcinoma (BCC) is the most common human malignancy, affecting 750 000
Americans each year. The understanding of mutations that are known to activate hedgehog …

Serrated colorectal carcinomas (CRCs) are morphologically different from conventional
CRCs and have been proposed to follow a distinct pathway of CRC formation. Despite …

Sonic hedgehog (Shh) was conditionally deleted in respiratory epithelial cells of the
embryonic lung in vivo. Deletion of Shh before embryonic day (E) 13.5 resulted in respiratory …

Adaptation to air breathing at birth is dependent on formation and function of the lung. Lung
morphogenesis is a complex process dependent on precise temporal–spatial control of cell …

Hedgehog (Hh) signaling is critical for embryonic development and in differentiation,
proliferation, and maintenance of multiple adult tissues. De-regulation of the Hh pathway is …

An abnormality in hedgehog (Hh) signaling has been implicated in the progression of
prostate cancer (PCa) to a more aggressive and therapy-resistant disease. Our assessments …

The Basal Cell Carcinoma (BCC) is a sort of unique tumour due to its combined peculiar
histological features and clinical behaviour, such as the constant binary involvement of the …

Nonunion is a serious complication of a bone fracture that may occur in any bone of the
skeletal system. It occurs when a broken bone fails to heal. Mesenchymal stem cell (MSC) …

Bone metastasis is the leading cause of tumor‐related deaths in patients with prostate
cancer (PCa). The interactions between PCa and the bone microenvironment form a vicious …