Biofilm is a complex structure of microbiome having different bacterial colonies or single type
of cells in a group; adhere to the surface. These cells are embedded in extracellular …

Most of the research on bacterial pathogenesis has focused on acute infections, but much
less is known about the pathogenesis of infections caused by bacteria that grow as …

The genus Mycobacterium includes human pathogens (Mycobacterium tuberculosis and
Mycobacterium leprae) and environmental organisms known as non-tuberculous …

Isoniazid (INH) was the first synthesized drug that mediated bactericidal killing of the
bacterium Mycobacterium tuberculosis, a major clinical breakthrough. To this day, INH …

Rifamycins are a class of antibiotics that were first discovered in 1957 and are known for
their use in treating tuberculosis (TB). Rifamycins exhibit bactericidal activity against many …

A number of non-tuberculous mycobacterium species are opportunistic pathogens and
ubiquitously form biofilms. These infections are often recalcitrant to treatment and require …

Recurrent tonsillitis is described as when an individual suffers from several attacks of
tonsillitis per year. Chronic and recurrent tonsillitis both cause repeated occurrences of …

Tuberculosis (TB) is a severe infectious disease worldwide. The increasing emergence of
drug‐resistant Mycobacterium tuberculosis (Mtb) has markedly hampered TB control …

Bacteria elicit an adaptive response against hostile conditions such as starvation and other
kinds of stresses. Their ability to survive such conditions depends, in part, on stringent …

There is an urgent need for new and better drugs to treat tuberculosis due to lengthy and
complex treatment regimens and a rising problem of drug resistance. Drug discovery efforts …